Comparison of objective optical quality measured by double-pass aberrometry in patients with moderate dry eye: Normal saline vs. artificial tears: A pilot study

Vandermeer, G.; Chamy, Y.; Pisella, Pierre‐Jean

doi:10.1016/j.jfo.2017.12.001

Cited by 19 publications

(13 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, HA is the active ingredient of many eye drops, such as DropStar ® by Bracco and Lubristil ® by Eyelab, which, hydrating the ocular surface and improving the quality of vision, are the mainstay to treat diseases such as dry eye syndrome and are useful at increasing the comfortability of contact lenses [56,222,223]. Many studies have proven the safety and the efficacy of native HA solutions as artificial tears [222,224,225,226]. More recently, also novel derivatives of hyaluronan with improved mechanical and biological properties are being investigated to formulate eye drops with enhanced ocular residence times.…”

Section: Applications Of Ha and Its Derivativesmentioning

confidence: 99%

Hyaluronic Acid in the Third Millennium

et al. 2018

View full text Add to dashboard Cite

Abstract:Since its first isolation in 1934, hyaluronic acid (HA) has been studied across a variety of research areas. This unbranched glycosaminoglycan consisting of repeating disaccharide units of N-acetyl-D-glucosamine and D-glucuronic acid is almost ubiquitous in humans and in other vertebrates. HA is involved in many key processes, including cell signaling, wound reparation, tissue regeneration, morphogenesis, matrix organization and pathobiology, and has unique physico-chemical properties, such as biocompatibility, biodegradability, mucoadhesivity, hygroscopicity and viscoelasticity. For these reasons, exogenous HA has been investigated as a drug delivery system and treatment in cancer, ophthalmology, arthrology, pneumology, rhinology, urology, aesthetic medicine and cosmetics. To improve and customize its properties and applications, HA can be subjected to chemical modifications: conjugation and crosslinking. The present review gives an overview regarding HA, describing its history, physico-chemical, structural and hydrodynamic properties and biology (occurrence, biosynthesis (by hyaluronan synthases), degradation (by hyaluronidases and oxidative stress), roles, mechanisms of action and receptors). Furthermore, both conventional and recently emerging methods developed for the industrial production of HA and its chemical derivatization are presented. Finally, the medical, pharmaceutical and cosmetic applications of HA and its derivatives are reviewed, reporting examples of HA-based products that currently are on the market or are undergoing further investigations.

show abstract

Section: Applications Of Ha and Its Derivativesmentioning

confidence: 99%

Hyaluronic Acid in the Third Millennium

et al. 2018

View full text Add to dashboard Cite

show abstract

“…The use of artificial tears is the most common therapeutic solution for dry eye syndrome. Tears based on HA and carmellose (carboxymethylcellulose) proved to be superior in terms of stability of the tear film and quality of vision in comparison with normal saline solution [ 26 , 50 , 51 , 52 , 53 , 54 ].…”

Section: Applications Of Hyaluronic Acidmentioning

confidence: 99%

Advantages of Hyaluronic Acid and Its Combination with Other Bioactive Ingredients in Cosmeceuticals

et al. 2021

View full text Add to dashboard Cite

This study proposes a review on hyaluronic acid (HA) known as hyaluronan or hyaluronate and its derivates and their application in cosmetic formulations. HA is a glycosaminoglycan constituted from two disaccharides (N-acetylglucosamine and D-glucuronic acid), isolated initially from the vitreous humour of the eye, and subsequently discovered in different tissues or fluids (especially in the articular cartilage and the synovial fluid). It is ubiquitous in vertebrates, including humans, and it is involved in diverse biological processes, such as cell differentiation, embryological development, inflammation, wound healing, etc. HA has many qualities that recommend it over other substances used in skin regeneration, with moisturizing and anti-ageing effects. HA molecular weight influences its penetration into the skin and its biological activity. Considering that, nowadays, hyaluronic acid has a wide use and a multitude of applications (in ophthalmology, arthrology, pneumology, rhinology, aesthetic medicine, oncology, nutrition, and cosmetics), the present study describes the main aspects related to its use in cosmetology. The biological effect of HA on the skin level and its potential adverse effects are discussed. Some available cosmetic products containing HA have been identified from the brand portfolio of most known manufacturers and their composition was evaluated. Further, additional biological effects due to the other active ingredients (plant extracts, vitamins, amino acids, peptides, proteins, saccharides, probiotics, etc.) are presented, as well as a description of their possible toxic effects.

show abstract

“…Moreover, HA is the active ingredient of many eye drops -such as DropStar® by Bracco and Lubristil® by Eyelab-which, hydrating the ocular surface, and improving the quality of vision, are the mainstay to treat diseases such as dry eye syndrome and are useful in increasing the comfortability of contact lenses [56,222,223]. Many studies have proved the safety and the efficacy of native HA solutions as artificial tears [222,[224][225][226].…”

Section: Ophthalmologic Surgery and Ophthalmologymentioning

confidence: 99%

“…Many studies have proved the safety and the efficacy of native HA solutions as artificial tears [222,[224][225][226]. More recently, also novel derivatives of hyaluronan with improved mechanical and biological properties are being investigated to formulate eye drops with enhanced ocular residence times.…”

Section: Ophthalmologic Surgery and Ophthalmologymentioning

confidence: 99%

Hyaluronic Acid in the 3<sup>rd</sup> Millennium

Fallacara¹,

Baldini²,

Manfredini³

et al. 2018

Preprint

View full text Add to dashboard Cite

Since its first isolation in 1934, hyaluronic acid (HA) has been studied across a variety of research areas. This unbranched glycosaminoglycan consisting of repeating disaccharide units of N-acetyl-D-glucosamine and D-glucuronic acid is almost ubiquitary in humans and in other vertebrates. HA is involved in many key processes -including cell signaling, wound reparation, tissue regeneration, morphogenesis, matrix organization and pathobiology-, and has unique physico-chemical properties -such as biocompatibility, biodegradability, mucoadhesivity, hygroscopicity and viscoelasticity. For these reasons, exogenous HA has been investigated as drug delivery system and treatment in cancer, ophthalmology, arthrology, pneumology, rhinology, urology, aesthetic medicine and cosmetic. To improve and customize its properties and applications, HA can be subjected to chemical modifications: conjugation and crosslinking. The present review gives an overview regarding HA, describing its history, physico-chemical, structural and hydrodynamic properties, and biology -occurrence, biosynthesis (by hyaluronan synthases), degradation (by hyaluronidases and oxidative stress), roles, mechanisms of action and receptors. Furthermore, both conventional and recently emerging methods developed for the industrial production of HA and its chemical derivatization are presented. Finally, the medical, pharmaceutical and cosmetic applications of HA and its derivatives are reviewed, reporting examples of HA-based products which currently are on the market or are undergoing further investigations.

show abstract

Comparison of objective optical quality measured by double-pass aberrometry in patients with moderate dry eye: Normal saline vs. artificial tears: A pilot study

Cited by 19 publications

References 22 publications

Hyaluronic Acid in the Third Millennium

Hyaluronic Acid in the Third Millennium

Advantages of Hyaluronic Acid and Its Combination with Other Bioactive Ingredients in Cosmeceuticals

Hyaluronic Acid in the 3<sup>rd</sup> Millennium

Contact Info

Product

Resources

About