Comparison of Ocular Biometry Using New Swept-source Optical Coherence Tomography-based Optical Biometer with Other Devices

Abstract

PurposeTo evaluate the agreement between optical biometry with swept-source optical coherence tomography-based optical biometry (IOLMaster 700) and other devices.MethodsA total of 137 eyes (78 patients) with cataracts were included in this retrospective study. Axial length (AL), anterior chamber depth (ACD), keratometry, and white-to-white (WTW) distance measured using IOLMaster 700 were compared with results for the following five different biometers: IOLMaster 500, A-scan, automated refractor, manual keratometry, and Galilei G4. Differences and correlations among the devices were assessed using the Bland-Altman plot and intraclass correlation coefficient (ICC).ResultsFor AL values, the IOLMaster 700, IOLMaster 500, and A-scan measurements showed excellent agreement (all ICC >0.99). For ACD values, ICC of IOLMaster 700 and Galilei G4 was 0.965 but A-scan was poorly correlated with either IOLMaster 700 or Galilei G4. The ICCs of IOLMaster 700 and other devices were all greater than 0.9 for average keratometry, but those of the mean cylinder keratometry were all between 0.7 and 0.8. The mean difference in the WTW distance between the IOLMaster 700 and Galilei G4 was 0.029 mm, but the ICC was 0.525. AL measurements were not possible for 10 eyes with the IOLMaster 500 but were obtained in all eyes with the IOLMaster 700.ConclusionsIn clinical practice, AL, ACD, and average keratometry values of IOLMaster 700 can be used interchangeably with those of the other devices tested. However, the ACD value between IOLMaster 700 and A-scan or the WTW distance between IOLMaster 700 and Galilei G4 are not interchangeable because of clinical and statistical differences in measurements between the devices.

Repeatability, reproducibility, and comparison of ocular biometry using a new optical coherence tomography-based system and another device

“…A high interclass correlation of 1 when measuring AL between IOLMaster 500 and 700 was observed. The mean difference between ACD measured by the two devices was only 0.08 mm, which is not clinically significant 2,11 . Another study assessed differences between IOLMaster 500 and Scheimpflug based camera Galileli G6 (Zimer, Port, Switzerland).…”

“…The recent clinical introduction of OCT-based biometers enabled identifying any irregularities in the eye anatomy such as lens tilt, macular edema, or central retinal detachment 11 . In this article, we used this new technology and analyzed the parameters in several significant ways.…”

“…Previous studies showed that the IOLMaster 500 has a high rate of correlation with the newer model of 700 with insignificant differences. One of the difference is the ability to penetrate denser cataracts, making it possible for a Swept-source light to measure through media opacities 2,11,12 . IOLMaster 500 was shown to be precise in both intersession and intrasession tests 13 .…”

Comparative Study between Optical and Ultrasonic Measurement of Axial Length and Anterior Chamber Depth in Normal, Long and Short Eyes

“…4 The updated IOL Master 700 (Carl Zeiss meditec, Germany) is a popular swept source optical tomography based optical biometer. 5 This SS-OCT is capable of obtaining multiple measurements in a single capture and generate AL abd ACD values with perfect alignation of subject's visual axis. 5 It uses a rapid-cycle, tunable wavelength laser to scan the eye, which improves the tissue penetration and image quality.…”

“…5 This SS-OCT is capable of obtaining multiple measurements in a single capture and generate AL abd ACD values with perfect alignation of subject's visual axis. 5 It uses a rapid-cycle, tunable wavelength laser to scan the eye, which improves the tissue penetration and image quality. 6 The ultrasound biometry using 10-MHz ultrasound waves to measure axial length and anterior chamber depth.…”