Comparison of the cellular composition of benign prostatic hyperplasia in chinese and caucasian-american men

Functional property, norepinephrine content and morphometric findings in human hyperplastic prostate

“…In this series, the percent area densities of the smooth muscle and glandular component were smaller than those reported previously [22,23]. Although histological detection of the smooth muscle depends on a method of histological staining, morphometric differences between the Asian population and Caucasian-American men also affect the results [24]. Present results demonstrate that there are apparent morphometric differences between Japanese and Chinese men with BPH.…”

Relationships between total/free prostate-specific antigen and prostate volume in Chinese men with biopsy-proven benign prostatic hyperplasia

“…Selection of patients in our study was similar to that in previous reports [10,11], so the difference may be attributed to the racial difference rather than selection bias. Some have reported that the cellular composition of BPH in the prostates of American and Chinese men is different [14,15], and this difference also exists among white American, black American, and Japanese men [16], resulting in racial differences in PSA, PSA density, and the incidence of clinical BPH. The slope of linear regression of PSA and PV was 3.68 in Korean men with biopsy-proven BPH reported by Lee et al [11], higher than in white men reported by Hochberg et al [7].…”

Morphometric analysis of pediatric and nonhyperplastic prostate glands: Evidence that BPH is not a unique stromal process

“…More recent studies have utilized computerassisted color image analysis to determine the histologic components of symptomatic and asymptomatic BPH specimens [8,13]. One of these studies examined the stromal elements in specimens from patients with symptomatic BPH and suggested that the severity of bladder outlet obstruction is dependent upon the density of smooth muscle [8].…”