Comparison of the Predictive Roles of Risk Scores of In-Hospital Major Adverse Cardiovascular Events in Patients with Non-ST Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention

Abstract

Significance of the Study• This study examines the relationship between risk scores and major adverse cardiovascular events (MACE) in patients with non-ST elevation myocardial infarction undergoing percutaneous coronary intervention. All risk scores were able to predict MACE, but the SYNTAX score II (SS-II) was also able to predict in-hospital mortality, nonfatal myocardial infarction, and stent thrombosis. The SS-II scoring system appears to be the most comprehensive scoring system as it is angiographic and has 6 clinical variables. The study population were selected from among 589 patients who underwent coronary angiography with a diagnosis of NSTEMI. TIMI and GRACE risk scores were calculated. SS and SS-II were calculated in all patients, and points were added according to the predefined algorithm, taking into account the other 6 clinical variables being monitored (age, sex, left ventricular ejection fraction, creatinine clearance, chronic obstructive pulmonary disease, and peripheral artery disease). Patients were classified into tertile 1 (SS < 22), tertile 2 (SS 23-32), and tertile 3 (SS > 32). Results: The group with high SS-II for PCI values in the risk scores were observed from tertile 1 to tertile 3 (from 25.0 ± 7.7 to 31.6 ± 9.4, p < 0.001, respectively). The SS-II score in patients with PCI was an independent predictor of MACE, in-hospital mortality, nonfatal myocardial infarction, and stent thrombosis (OR 1.082, 95% CI 1.036-1.131, p < 0.001). The overall MACE, inhospital mortality, and nonfatal myocardial infarction rates

The Association of Fractional Pulse Pressure with Acute Kidney Injury in Patients Undergoing Coronary Intervention due to ST-Segment Elevated Myocardial Infarction

“…Peripheral arterial disease was also significantly associated with major adverse cardiac events in acute coronary syndrome patients [21]. Higher SYN-TAX scores have been correlated with AKI development, more adverse cardiac events, and the need for hemodialysis in patients with acute coronary syndrome [22,23]. In parallel with the literature, in the current study, the SYNTAX score was higher in patients with AKI than those without.…”

Association of GRACE Risk Score with Coronary Artery Disease Complexity in Patients with Acute Coronary Syndrome

“…Several studies have previously reported the positive correlation between the GRACE score and other CAD severity assessment tools [12,13,[16][17][18][19][36][37][38][39][40]. Specifically, Hammami et al found that the GRACE score was significantly higher in UA and NSTEMI patients with a SYNTAX score ≥ 33, with a weak positive correlation reported between the two scores (r = 0.23) [16].…”

Investigation of the Effect of HATCH Score and Coronary Artery Disease Complexity on Atrial Fibrillation after On-Pump Coronary Artery Bypass Graft Surgery

“…The SYNTAX (synergy between percutaneous coronary intervention with taxus and cardiac surgery) score I is an angiographic scoring system that indicates the severity of coronary artery disease. It is commonly utilized to assess long-term results after percutaneous coronary interventions and CABG surgery [4, 5]. In patients undergoing CABG, extensive coronary artery disease has been shown to be an additional risk factor for the occurrence of PoAF [6].…”