Comparison of Three Methods for Measuring Nasal Mucociliary Clearance in Man

Puchelle, Édith; F, Aug; Pham, Q T; Bertrand, Alain

doi:10.3109/00016488109138511

Cited by 106 publications

(71 citation statements)

References 9 publications

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“…Nasal mucociliary transit time (NMTT) assessment has been done using different materials including radioactive markers, insoluble charcoal and micro alluminum discs. In a study comparing three of the common methods, Puchelle et al [5], validated the suitability of using saccharin as a simple screening test for nasal mucociliary clearance times. As a consequence, commercially available medical grade saccharin sweetener was used which is both easily available and inexpensive.…”

Section: Discussionmentioning

confidence: 99%

Impact of Nasal Symptoms on the Quality of Life of Fresh Inductees in High Altitude

Datta

Panwar

2008

Medical Journal Armed Forces India

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Background: Troops deployed in high altitude areas of Ladakh face nasal problems in the form of obstructive nasal symptoms and recurrent epistaxis. This study analyses the changes in the nasal mucociliary transit times (NMTT) and deterioration in quality of life of troops on first high altitude induction. Methods: A prospective study on 100 healthy volunteers was done. Mucociliary transit time was measured and a standardized quality of life questionnaire (RQLQ) administered at onset and after a period of three months in high altitude. Thereafter the subjects were divided into two groups and the study group was administered normal saline nasal drops. The observations were taken and results were statistically analysed after a period of three months. Result: The mucociliary transit time was prolonged after a three month stay in high altitude (p< 0.005). Normal saline nasal drops were successful in improving the nasal mucociliary transit times (p < 0.05). There was a statistically significant derangement in the quality of life which was improved by administering normal saline nasal drops (p<0.05). Conclusion: An increased muco-cilliary transport time after exposure to high altitude denotes a deranged physiology of the nasal mucosa. This leads to a statistically significant adverse impact on the quality of life of the troops deployed. The use of normal saline nasal drops is a simple and effective method of reversing some of these changes. MJAFI 2008; 64 : 214-217

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Section: Discussionmentioning

confidence: 99%

Impact of Nasal Symptoms on the Quality of Life of Fresh Inductees in High Altitude

Datta

Panwar

2008

Medical Journal Armed Forces India

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“…In the statistics reviewed, [1][2][3][5][6][7][8][9][10] we found that the sample sizes varied from a minimum of 20 to a maximum of 50. Hence, we (based on feasibility) studied a total of 32 subjects in each of the groups (chronic rhinosinusitis, smokers, and controls); a total of 96 subjects were studied.…”

Section: Methodsmentioning

confidence: 99%

Mucociliary Function: Its Variations with Disease

Kumar¹,

Preetham²,

Feshan³

2016

An International Journal Clinical Rhinology

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Introduction: This study compares the nasal mucociliary clearance time of patients with chronic sinusitis (pre-and postoperatively) and smokers, with controls, attending the ear, nose, and throat outpatient department at Southern Railway Headquarters Hospital, Perambur, Chennai. Materials and methods:Saccharin granule was used to study mucociliary clearance as it is safe, easy, fast, and reliable. A total of 32 patients in each group were studied. In chronic rhinosinusitis patients, the test was done preoperatively and 4 weeks postoperatively. Results:The average mucociliary clearance time pre-and postoperatively in chronic rhinosinusitis patients was 29.54 ± 28.68 and 12.17 ± 5.84 respectively. Cigarette smokers had a longer mucociliary clearance time (27.63 ± 21.11) compared with beedi smokers (24.04 ± 24.93). Controls had the fastest mucociliary clearance rate of 9.67 ± 4.62 among the study subjects.Conclusion: Surgery for chronic rhinosinusitis improves both the overall symptoms of chronic rhinosinusitis and the protective functions of the nose and paranasal sinuses. Smokers had an impaired clearance rate compared with normals. As age advances, the mucociliary clearance rate becomes slower.

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“…MC was evaluated calculating the time needed by saccharine crystals to reach the rhynopharynx, as this method has been demonstrated to be as reliable as the radioisotopic one [44]. It has been suggested, in a recent paper [40], to add charcoal powder to 3% saccharine, in order to increase information about the real mucociliary transport time.…”

Section: Methodsmentioning

confidence: 99%

Mucociliary function and nasal resistance evaluation before and after adenoidectomy

Maurizi

Paludetti

Ottaviani

et al. 1986

International Journal of Pediatric Otorhinolaryngology

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Thirty-four children with clinically and radiologically confirmed adenoid hypertrophy underwent otoscopy, impedance tests, active anterior rhinomanometry and nasal mucociliary clearance evaluation before and 6 months after adenoidectomy. Mucociliary clearance velocity increased significantly while binasal resistances decreased after surgery. The authors conclude that mucociliary evaluation and objective measurements of nasal resistances should be added to impedance tests as indicators to adenoidectomy

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Comparison of Three Methods for Measuring Nasal Mucociliary Clearance in Man

Abstract: Abstracf. Three techniques for studying nasal mucociliary clearance have been compared in 20 normal subjects, aged 19 to 26. Three different tracers used were deposited on Acta Otolatyngol9l

Cited by 106 publications

References 9 publications

Impact of Nasal Symptoms on the Quality of Life of Fresh Inductees in High Altitude

Impact of Nasal Symptoms on the Quality of Life of Fresh Inductees in High Altitude

Mucociliary Function: Its Variations with Disease

Mucociliary function and nasal resistance evaluation before and after adenoidectomy

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