Comparison of tooth derived hydroxyapatite with commercially pure hydroxyapatite

Azariah, E.D.S.; Evangeline, A.; Chinnasami, R.

doi:10.1016/j.ijom.2017.02.1228

Cited by 2 publications

(2 citation statements)

References 2 publications

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“…Dentin derived hydroxyapatite (DDHA) is attracting attention as bone graft material and titanium surface coating material for osseointegration, because it contains more osteoinductive component than commercially available HA [4]. In this study, DDHA coating with RF magnetron method was performed on titanium surface and surface characteristics was observed.…”

Section: Discussionmentioning

confidence: 99%

Surface Characteristics of Dentin Derived Hydroxyapatite Coated Layer on Titanium by RF Magnetron Sputtering

Moon

Kim

2018

KEM

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The aim of this study was to evaluate surface characteristics and biological properties of the dentin derived hydroxyapatite (DDHA) coating on titanium substrate. DDHA was derived from extracted human teeth with calcination method at 850°C. The commercially pure titanium was used as a metallic substrate and a RF magnetron sputtering method was used as a coating method. Scanning Electron Microscopy (SEM) and Energy Dispersive X-ray analysis (EDX) were performed to investigate the morphology and composition of coating surface. Atomic Forced Microscopy (AFM) and surface profiler were used to assess the surface morphology and roughness. Corrosion tests were performed in phosphate buffered saline at a 36.5±1°C in order to determine the corrosion behavior of the uncoated and coated surface samples. The biocompatibility of DDHA coating surface samples with murine osteoblastic cells was assessed by SEM. As a results, thin coating layer was observed on SEM images and uniformly cover the surfaces without change of titanium substrate. The EDX analysis of this coating surface indicated the presence of Ca, P elements. The mean surface roughness of cp-Ti and DDHA coating samples was 0.27μm, 1.7μm, respectively. The corrosion test indicated the stable passive film on coating samples. SEM observations of murine osteoblastic cells on coating surface showed that cells have proliferated and developed a network of dense interconnections. These results suggest that DDHA coating with RF magnetron sputtering method has good surface characteristics and biocompatibility.

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Section: Discussionmentioning

confidence: 99%

Surface Characteristics of Dentin Derived Hydroxyapatite Coated Layer on Titanium by RF Magnetron Sputtering

Moon

Kim

2018

KEM

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“…The dental matrix contains HA and type 1, type 3 and type 5 collagen, and proteins are very similar to alveolar bone as they are both derived from the cells of the neural crest [ 55 , 96 , 97 , 98 ]. The hydroxyapatite present in the dental matrix has the same composition of HA as that present in bone, and for this reason, it is similar to the synthetic one [ 99 ]. The osteoconductive properties of tooth-derived materials are widely accepted by several authors [ 96 , 100 , 101 ].…”

Section: Bone Substitutes and Graftmentioning

confidence: 99%

Innovative Concepts and Recent Breakthrough for Engineered Graft and Constructs for Bone Regeneration: A Literature Systematic Review

et al. 2022

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Background: For decades, regenerative medicine and dentistry have been improved with new therapies and innovative clinical protocols. The aim of the present investigation was to evaluate through a critical review the recent innovations in the field of bone regeneration with a focus on the healing potentials and clinical protocols of bone substitutes combined with engineered constructs, growth factors and photobiomodulation applications. Methods: A Boolean systematic search was conducted by PubMed/Medline, PubMed/Central, Web of Science and Google scholar databases according to the PRISMA guidelines. Results: After the initial screening, a total of 304 papers were considered eligible for the qualitative synthesis. The articles included were categorized according to the main topics: alloplastic bone substitutes, autologous teeth derived substitutes, xenografts, platelet-derived concentrates, laser therapy, microbiota and bone metabolism and mesenchymal cells construct. Conclusions: The effectiveness of the present investigation showed that the use of biocompatible and bio-resorbable bone substitutes are related to the high-predictability of the bone regeneration protocols, while the oral microbiota and systemic health of the patient produce a clinical advantage for the long-term success of the regeneration procedures and implant-supported restorations. The use of growth factors is able to reduce the co-morbidity of the regenerative procedure ameliorating the post-operative healing phase. The LLLT is an adjuvant protocol to improve the soft and hard tissues response for bone regeneration treatment protocols.

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Comparison of tooth derived hydroxyapatite with commercially pure hydroxyapatite

Cited by 2 publications

References 2 publications

Surface Characteristics of Dentin Derived Hydroxyapatite Coated Layer on Titanium by RF Magnetron Sputtering

Surface Characteristics of Dentin Derived Hydroxyapatite Coated Layer on Titanium by RF Magnetron Sputtering

Innovative Concepts and Recent Breakthrough for Engineered Graft and Constructs for Bone Regeneration: A Literature Systematic Review

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