Competition among the attentional networks due to resource reduction in Tibetan indigenous residents: evidence from event-related potentials

Zhang, De‐Long; Zhang, Sheng; Ma, Hua; Wang, Yan; Ma, Huifang; Liu, Ming

doi:10.1038/s41598-017-18886-7

Cited by 29 publications

(27 citation statements)

References 39 publications

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“…RRN is a subcluster of the P3 component, which is an indicator of the brain's cognitive resources (Ma et al, 2016 ). It is directly related to the brain's executive control ability under hypoxia (Ma et al, 2015a , b ; Zhang et al, 2018 ). However, the underlying neural activity of this executive control system is still unclear.…”

Section: Introductionmentioning

confidence: 99%

Decreased Event-Related Desynchronization of Mental Rotation Tasks in Young Tibetan Immigrants

Zu-qiang

Huang

Luo

et al. 2021

Front. Hum. Neurosci.

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The present study aimed to explore the cortical activity underlying mental rotation in high-altitude immigrants via the event-related desynchronization (ERD), the electroencephalogram time–frequency analysis, and source localization based on electroencephalographic data. When compared with the low-altitude individuals, the reaction time of mental rotation tasks was significantly slower in immigrants who had lived in high-altitude areas for 3 years. The time–frequency analysis showed that the alpha ERD and the beta ERD within the time window (400–700 ms) were decreased during the mental rotation tasks in these immigrants. The decreased ERD was observed at the parietal–occipital regions within the alpha band and at the central–parietal regions within the beta band. The decreased ERD might embody the sensorimotor-related cortical activity from hypoxia, which might be involved in cognitive control function in high-altitude immigrants, which provided insights into the neural mechanism of spatial cognition change on aspect of embodied cognition due to high-altitude exposure.

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Section: Introductionmentioning

confidence: 99%

Decreased Event-Related Desynchronization of Mental Rotation Tasks in Young Tibetan Immigrants

Zu-qiang

Huang

Luo

et al. 2021

Front. Hum. Neurosci.

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“…Moreover, individuals inhabiting extremely high altitudes (over 4,000 m), showed lower levels of performance in all executive tests (Virués-Ortega et al, 2011). However, in contrast, three different electrophysiological studies (Ma et al, 2015a; Richardson et al, 2011; Singh et al, 2004), reported that the influence of high altitude on cognition was present at altitudes above and below 4,000 m. Our previous study (Zhang et al, 2018), based on the attention network test (ANT), compared individuals residing at 2,900 m and 3,700 m with those residing at 4,200 m. The latter had lower orienting and executive function scores. They had larger N1 and P3 amplitudes than individuals in the other groups, which suggested that high-altitude could affect attentional function in individuals indigenous to different high-altitude areas and that a threshold may exist at 4,000 m (Zhang et al, 2018).…”

Section: Introductionmentioning

confidence: 71%

Different neurocognitive patterns of conflict control in Tibetans living above and below 4,000 m

Han

Wang

2019

PeerJ

Self Cite

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Background The existence of a particular threshold of hypoxia severity, beyond which neuropsychological functioning is compromised, is unclear. We investigated the neurocognitive profile related to conflict control in healthy young Tibetans born and living at three different altitudes (2,700 m, 3,700 m, and 4,500 m) in Tibet to investigate the existence of this threshold. Methods Using event-related potentials (ERPs), the conflict control functions of individuals in the three altitude groups were investigated by means of a flanker task, using congruent and incongruent stimuli. The data were analyzed using mixed-model analyses of variance. Results Although effect of altitude was not significant at a behavioral level (p > 0.05), the ERPs showed cognitive conflict modulation. The N2 difference wave (for incongruent minus congruent conditions) was smaller in the 4,500-m group than in the groups living below 4,000 m (p < 0.05). The study’s findings suggest that the influence of high altitude in the conflict monitoring stage becomes significant above 4,000 m. Thus, the altitude threshold for impairment of cognition may be 4,000 m.

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“…Behavior and brain structure changes arising from hypoxia can be observed in a real high-altitude environment, and examined in simulated hypoxia situations. The hypoxia impact on the brain exhibits a significant altitude-dependent effect [5,6].…”

Section: Introductionmentioning

confidence: 99%

Changes in Hippocampus and Amygdala Volume with Hypoxic Stress Related to Cardiorespiratory Fitness under a High-Altitude Environment

Wang

et al. 2022

Brain Sciences

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The morphology of the hippocampus and amygdala can be significantly affected by a long-term hypoxia-induced inflammatory response. Cardiorespiratory fitness (CRF) has a significant effect on the neuroplasticity of the hippocampus and amygdala by countering inflammation. However, the role of CRF is still largely unclear at high altitudes. Here, we investigated brain limbic volumes in participants who had experienced long-term hypoxia exposure in Tibet (3680 m), utilizing high-resolution structural images to allow the segmentation of the hippocampus and amygdala into their constituent substructures. We recruited a total of 48 participants (48 males; aged = 20.92 ± 1.03 years) to undergo a structural 3T MRI, and the levels of maximal oxygen uptake (VO2max) were measured using a cardiorespiratory function test. Inflammatory biomarkers were also collected. The participants were divided into two groups according to the levels of median VO2max, and the analysis showed that the morphological indexes of subfields of the hippocampus and amygdala of the lower CRF group were decreased when compared with the higher CRF group. Furthermore, the multiple linear regression analysis showed that there was a higher association with inflammatory factors in the lower CRF group than that in the higher CRF group. This study suggested a significant association of CRF with hippocampus and amygdala volume, which may be related to hypoxic stress in high-altitude environments. A better CRF reduced physiological stress and a decrease in the inflammatory response was observed, which may be related to the increased oxygen transport capacity of the body.

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Competition among the attentional networks due to resource reduction in Tibetan indigenous residents: evidence from event-related potentials

Cited by 29 publications

References 39 publications

Decreased Event-Related Desynchronization of Mental Rotation Tasks in Young Tibetan Immigrants

Decreased Event-Related Desynchronization of Mental Rotation Tasks in Young Tibetan Immigrants

Different neurocognitive patterns of conflict control in Tibetans living above and below 4,000 m

Changes in Hippocampus and Amygdala Volume with Hypoxic Stress Related to Cardiorespiratory Fitness under a High-Altitude Environment

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