Complementary and Alternative Approaches to Menopause

Taylor, Maida

doi:10.1016/j.ecl.2015.05.008

Cited by 41 publications

(32 citation statements)

References 75 publications

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“…Hop extracts are in some dietary supplements used for managing menopausal symptoms [54]. The most potent phytoestrogen in hops is the ERα-selective agonist 8-prenylnaringenin (8-PN), which is 100-fold more potent than the ERβ-selective isolavones genistein and daidzein [33].…”

Section: Clinical Studiesmentioning

confidence: 99%

“…(Brassicaceae), it is used for hormonal balance, especially for menopausal symptoms [54]. Albeit the active phytoestrogen has not been detected, the extract of maca showed estrogenic efect increasing proliferation in MCF-7 cells.…”

Section: Clinical Studiesmentioning

confidence: 99%

“…The most potent phytoestrogen in hops is the ERα-selective agonist 8-prenylnaringenin (8-PN), which is 100-fold more potent than the ERβ-selective isolavones genistein and daidzein [33]. Clinical trials suggest positive results of 8-PN in reducing the symptoms of menopause [54] however due to their high ainity to ERα; it is important to evaluate the safety on the endometrium and other hormone-sensitive tissues [33].…”

Section: Clinical Studiesmentioning

confidence: 99%

“…Rhubard is a plant used for menopausal symptoms relief in Germany [54]. The extract from roots of rhubard mainly consists of rhaponticin and desoxyrhaponticin, which are converted to the resveratrol-like aglycones rhapontigenin and desoxyrhapontigenin by the microbiome.…”

Section: Clinical Studiesmentioning

confidence: 99%

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Use of Phytoestrogens for the Treatment of Psychiatric Symptoms Associated with Menopause Transition

Estrada‐Camarena¹,

López‐Rubalcava²,

Sustaita³

et al. 2017

A Multidisciplinary Look at Menopause

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Menopause transition is recognized as a vulnerable period in women life to develop or aggravate symptoms of psychiatric disorders. Several treatments including antidepressants and hormonal restitution with estrogens have been suggested to ameliorate the symptoms. Also, in this period of life is frequent the use of other drugs to treat is also frequent the use of other drugs to treat comorbid pathologies that might even increase the risk of drug-drug interactions. Literature reports that some phytochemicals with estrogenic activity have beneicial efects during menopausal transition without collateral events. This chapter shows evidence about the use of phytoestrogens as an alternative therapy for the treatment of some psychiatric symptoms associated with the menopausal transition. Data derived from preclinical research related to the use of classical phytoestrogens (isolavones), considering the beneicial efects, as well as adverse events, are discussed. Also, the use of polyphenols and organosulfurate compounds as an alternative for the treatment of anxiety-and depressive-like behavior as well as ibromyalgia is included. A narrative review was conducted using bibliography reporting the use of isolavones (genistein, daidzein, equol), coumestans or lignans for the reduction of depressive-like or anxiety-like behavior. Furthermore, it is described if the use of this compounds impact in other signs of menopause, i.e. vasomotor and osteoporosis. In addition, due to the high frequency of comorbid pathologies as diabetes mellitus, dyslipidemia or metabolic syndrome with psychiatric disorders, the use of these phytochemicals is discussed.

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Section: Clinical Studiesmentioning

confidence: 99%

Section: Clinical Studiesmentioning

confidence: 99%

Section: Clinical Studiesmentioning

confidence: 99%

Section: Clinical Studiesmentioning

confidence: 99%

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Use of Phytoestrogens for the Treatment of Psychiatric Symptoms Associated with Menopause Transition

Estrada‐Camarena¹,

López‐Rubalcava²,

Sustaita³

et al. 2017

A Multidisciplinary Look at Menopause

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“…Essa planta é a mais estudada, dentro do grupo dos fitoestrogênicos, principalmente como isoflavonas como glicosídeos (genisteína e daidzeína) que são hidrolisadas no intestino formando agliconas seletivas do receptor estrogênico (RE). (JIA et al, 2012;TAYLOR, 2015, LOPEZ-GUTIERREZ et al, 2014. Na mucosa intestinal, a microflora metaboliza a daidzeína em S-quol que apresenta melhor atividade estrogênica e alta afinidade para o RE que a daidzeína levando a efeitos estrógeno-símile melhorando os sintomas do climatério (DIETZ et al, 2016).…”

Section: As Plantas Medicinais Que Podem Ser Utilizadas Para Tratamenunclassified

Caracterização Das Plantas Medicinais E Medicamentos Fitoterápicos Para Tratamento Da Osteoporose Utilizados No Brasil

Marques

Lima

Andreotti

et al. 2016

Arq. Ciênc. Saúde Unipar

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Caracterização das plantas medicinais e medicamentos fitoterápicos para tratamento da osteoporose utilizados no Brasil. Arq. Cienc. Saúde UNIPAR, Umuarama, v. 20, n. 3, p, 183-188, set./dez. 2016. RESUMO:A osteoporose é caracterizada por desordem do sistema esquelético caracterizada por baixa massa óssea e deteriorização da microarquitetura do tecido ósseo levando a fragilidade óssea com aumento da suscetibilidade a fraturas. Considerada a doença osteometabólica mais comum, de distribuição global, pode comprometer ambos os sexos, diferentes idades ou raças. As consequências relacionadas a essas doenças são as fraturas vertebrais verificadas em aproximadamente 20% das mulheres acima de 65 anos em pós-menopausa. Além disso, a consequência dessa fragilidade óssea pode levar a consequências graves como dor, deformidades, sequelas, restrições motoras e morte precoce, portanto, associada com alta morbi/mortalidade. Desta forma, sabendo que as medicações utilizadas para o tratamento da osteoporose não são isentas de risco (por exemplo, aumento do risco de tromboses, câncer de mama/ ovário/ endométrio, lesões musculares, entre outras), foi realizado uma revisão bibliográfica com o intuito de avaliar se existem plantas medicinais que possam ter efeitos ósseo protetores com menor número de efeitos adversos em relação aos fármacos sintéticos. Em síntese, verificou-se que os fármacos sintéticos podem acarretar prejuízos à saúde do paciente a longo prazo e que as plantas medicinais ou fitoterápicos utilizadas no Brasil apresentam estudos científicos com menores efeitos colaterais e, portanto, são uma alternativa viável para o tratamento e prevenção da osteoporose, visto que a Politica Nacional de Práticas Integrativas e Complementares na Atenção Básica sustenta esta tendência mediante subsídios como a Farmacopeia Brasileira e o Memento Fitoterápico. PALAVRAS-CHAVE: Brasil. Fitoterapia. Medicamentos Fitoterápicos. Osteoporose. CHARACTERIZATION OF MEDICINAL PLANTS AND HERBAL MEDICINES FOR THE TREATMENT OF OSTEOPOROSIS USED IN BRAZILABSTRACT: Osteoporosis is characterized by skeletal system disorder, consisting of low bone mass and deterioration of the microarchitecture of the bone tissue, leading to bone fragility with increased susceptibility to fractures. Considered the most common osteometabolic disease worldwide, it affects both sexes, different ages and races. The consequences of these diseases are vertebral fractures in approximately 20% of postmenopausal women over 65 years of age. In addition, the consequence of this bone fragility may lead to serious consequences, such as pain, deformities, sequelae, motor restrictions and early death, being therefore associated with high morbidity/mortality. Therefore, knowing the medication used in the treatment of osteoporosis are not free of risk (for example, increased risk of thrombosis, breast/ovarian/endometrial cancer, muscle injuries, among others), a bibliographical review was made with the intent of evaluating whether there are medicinal plants that may have protective ef...

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Bioactive Phytochemicals from Evening Primrose (Oenothera biennis) Oil-processing By-products

Durazzo

Lucarini

Lena

et al. 2022

Reference Series in Phytochemistry

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Complementary and Alternative Approaches to Menopause

Cited by 41 publications

References 75 publications

Use of Phytoestrogens for the Treatment of Psychiatric Symptoms Associated with Menopause Transition

Use of Phytoestrogens for the Treatment of Psychiatric Symptoms Associated with Menopause Transition

Caracterização Das Plantas Medicinais E Medicamentos Fitoterápicos Para Tratamento Da Osteoporose Utilizados No Brasil

Bioactive Phytochemicals from Evening Primrose (Oenothera biennis) Oil-processing By-products

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