Complementary and Alternative Approaches to Treat Peptic Ulcer

Abstract

Peptic ulcer is considered as one of the most common disorder among gastrointestinal ailments all over the world which is mainly caused by Helicobacter pylori infection, abundant use of NSAIDs, excessive alcohol intake and stress etc. Treatment of peptic ulcer with synthetic drugs such as proton pump inhibitors, H2 receptor antagonists and other non-steroidal anti-inflammatory drugs reported to have adverse effects, relapses and drug interactions. Medicinal plants containing active phyto-constituents have been proven as useful source in the prevention and treatment of various diseases including gastrointestinal problems. Demands of herbal medicines are increasing in both developed and developing countries due to growing recognition of natural plants having lesser or no side effects, relatively less toxic, economical and easily available in surrounding place. Therefore, medicinal plants stand out as being exceptional for its ethnic, ethno botanical and ethno pharmaceutical uses. In this review an attempt has been made to compile some plants which may be used in treatment or prevention of peptic ulcers. This article summarizes the antacid, anti-ulcer and gastro protective properties of the most commonly available medicinal plants.

GC-MS, FTIR and Antiulcer Screening of Aqueous Seed Extract and Oil of Nigella sativa in Wistar Rats

“…Gastric ulcer is due to an imbalance between protective and aggressive factors in the stomach, which is caused by the infection of Helicobacter pylori 29 , non-steroid antiinflammatory drugs, stress condition, and alcohol consumption 30,31 . Microscopic and pharmacognostic standardization will help in the identification and authentication of the genuine plant materials, the presence of starch grains, Lignified tissues, cellulose, proteins, and oil globules, as shown in tables 1 and 2.…”

Pengaruh Ekstrak Minyak Jintan Hitam (Nigella Sativa) terhadap Mukosa Lambung Mencit (Mus Musculus) yang Diinduksi Etanol 80%

“…Ulkus Lambung bertujuan untuk mengurangi nyeri, mengobati ulkus, dan mencegah terjadinya ulkus berulang, serta mencegah komplikasi (Al et al, 2008;Paguigan et al 2014;Taringan & Akil, 2009 (Sultana et al, 2014). Olehnya itu, perlu dikembangkan usaha untuk menemukan pengobatan yang efektif dan bersumber dari alam (Adinortey et al, 2013;Hasan et al, 2014;Agus S et al, 2011).…”

Impact of habitat variability on growth dynamics of Bergenia ciliata (Haw.) Sternb. along an altitudinal gradient in Kashmir Himalaya

“…The plant species shows many important biological activities such as antioxidant, anti-inflammatory, antitussive, antiviral, antiulcer, hypoglycemic and toxicological activities (19 21). It is a potent source of flavonoids, saponins, alkaloids, amino-acids and carbohydrates (22). Bergenin and its glycosides, (+)-Catechin, Gallic acid and leucocyanidin, Paashaanolactone, β-Sitosterol -Afzelechin are some of the important phytochemicals of B. ciliata (23).…”