Complementary and alternative medicine

Bellanger, Renee A.; Seeger, Christina

doi:10.1016/bs.seda.2021.07.003

Cited by 6 publications

(1 citation statement)

References 69 publications

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“…Ashwagandha or winter cherry (Withania somnifera L. Dunal, family Solanaceae), the evergreen shrub, is originated to the Middle East, India, and parts of Africa (Bellanger;Seeger 2021;Gupta et al, 2021). W. somnifera in traditional medicine has many applications such as antitumor, immunomodulatory, antiarthritic, antioxidant, hepatoprotective and anti-inflammatory activities (Bhattacharya et al, 2002;Harikrishnan et al, 2008;Jacobs;Pierce 2018).…”

Section: Introductionmentioning

confidence: 99%

GC-MS and HPLC analyses of phytochemical compounds from Withania somnifera L. leaves extract

EL-Hefny

El-Kareem

Salem

2022

Alexandria Journal of Agricultural Sciences

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In the present work, the shrub W. somnifera was used as a source for the extraction of bioactive molecules. Leaves were extracted by ethanol and analyzed by Gas Chromatography-Mass Spectrometry (GC-MS) and High-Performance Liquid Chromatography (HPLC). By GC-MS analysis, the highest identified compounds were 2,6-dimethyl-N-(2-methylα-phenylbenzyl)aniline, 4-Aminoheptane, n-undecanophenone, 2-cyclohexyl-4-hydroxymethyl-octahydrobenzo[e][1,2] oxazine-3-carbonitrile, and octadecanoic acid 3-octadecyloxypropyl ester, with percentages of 19.43%, 7.51%, 4.47%, 4.34%, and 3.89%, respectively. HPLC analysis identified quercetin and 7-hydroxyflavone with concentrations of 12.36 and 15.14 mg/mL, respectively, as two flavonoid compounds. This work showed that W. somnifera leaf extract owns several bioactive compounds that could be useful and have different applications, such as antimicrobial activities.

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