Complementary Performance of Organoselenides and Organotellurides as Antimicrobials Agents

Borges, Felipe G.; Zugman, Tay; Bandeira, Pamela T.; Dalmolin, Mara C.; Scariot, Débora B.; Garcia, Francielle P.; Oliveira, Alfredo R. M. de; Nakamura, C. V.; Piovan, Leandro

doi:10.21577/0103-5053.20200201

Cited by 2 publications

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“…In addition, due to their unique physical and chemical properties, many of these compounds have been used as versatile building blocks in the synthesis of complex organic molecules, biologically active compounds, pharmaceuticals, and natural products [14][15][16]. From the viewpoint of biological activities, organochalcogen compounds are known by their antioxidant [17,18], antitumoral [19][20][21], antimicrobial [22,23], and anti-inflammatory activities [24]. Several are heterocyclic systems containing sulfur on its structure available as FDA-approved drugs [25,26].…”

Section: Introductionmentioning

confidence: 99%

Recent Approaches in Transition Metal-Catalyzed Chalcogenative Heteroannulation of Alkenes and Alkynes

Gutterres,

Anjos,

Santos

et al. 2023

Catalysts

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Organochalcogen-bearing heterocycles are important scaffolds in compounds under the spotlight of scientific interest in optoelectronic fields and for biological applications. The use of transition metals has been a versatile and reliable way to carry out the synthesis of these molecules efficiently, delivering products in high yields and with a wide functional diversity. In the last 10 years, many classes of heterocycles have been synthesized under the cyclization reaction of acyclic alkenes and alkynes with the incorporation of a chalcogen atom on its structure. Transition metal catalysts including Cu, Co, Pd, Ni, In, Ag, and Fe salts have been used in the development of new methodologies, the expansion of substrate scope, and mechanistic studies. This review provides an overview of these recent approaches with the aim of being a useful resource for interested researchers in this area.

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Section: Introductionmentioning

confidence: 99%

Recent Approaches in Transition Metal-Catalyzed Chalcogenative Heteroannulation of Alkenes and Alkynes

Gutterres,

Anjos,

Santos

et al. 2023

Catalysts

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“…Compounds containing chalcogen elements-for instance, selenium, tellurium, and sulphur-have wide applications in many areas of science [1][2][3]. Importantly, they can act as redox centers and modulate the activity of biomolecules [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Rational Design and Synthesis of Large Stokes Shift 2,6-Sulphur-Disubstituted BODIPYs for Cell Imaging

et al. 2022

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Five new disubstituted 2,6-thioaryl-BODIPY dyes were synthesized via selective aromatic electrophilic substitution from commercially available thiophenols. The analysis of the photophysical properties via absorption and emission spectroscopy showed unusually large Stokes shifts for BODIPY fluorophores (70–100 nm), which makes them suitable probes for bioimaging. Selected compounds were evaluated for labelling primary immune cells as well as different cancer cell lines using confocal fluorescence microscopy.

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Complementary Performance of Organoselenides and Organotellurides as Antimicrobials Agents

Cited by 2 publications

References 0 publications

Recent Approaches in Transition Metal-Catalyzed Chalcogenative Heteroannulation of Alkenes and Alkynes

Recent Approaches in Transition Metal-Catalyzed Chalcogenative Heteroannulation of Alkenes and Alkynes

Rational Design and Synthesis of Large Stokes Shift 2,6-Sulphur-Disubstituted BODIPYs for Cell Imaging

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