Complete Genome Sequence of Trueperella pyogenes, Isolated from Infected Farmland Goats

Zhang, Su-Hui; Qiu, Jianping; Yang, Rui; KeFei, Shen; Xu, Guoyang; Fu, Lizhi

doi:10.1128/genomea.01421-16

Cited by 5 publications

(6 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Biofilm production was noted in a majority of the studied T. pyogenes isolates from different animal species and various types of infections [43,134]. Biofilm formation by T. pyogenes is controlled by a two-component regulatory system PloS/PloR, where PloR up-regulates the expression of biofilm [64,179,209]. In the case of polymicrobial infection, a biofilm formation by T. pyogenes may be inhibited by the QS molecules produced by other bacteria, for example E. coli [64,210].…”

Section: Pathogenesis Of T Pyogenes Infectionmentioning

confidence: 99%

“…Apart from the virulence-associated genes, the genome of this species can contain several antibiotic resistance genes. Furthermore, the lux S gene regulating the formation of biofilms was also found in the genome sequence [209]. In addition, the presence of a member of the T4virus (vB_EcoM-UFV13) indicates the efficiency in controlling the biofilm formation by T. pyogenes [216].…”

Section: T Pyogenes Genomementioning

confidence: 99%

See 1 more Smart Citation

Pathogenicity and Virulence of Trueperella pyogenes: A Review

Rzewuska

Kwiecień

Chrobak-Chmiel

et al. 2019

IJMS

127

110

View full text Add to dashboard Cite

Bacteria from the species Trueperella pyogenes are a part of the biota of skin and mucous membranes of the upper respiratory, gastrointestinal, or urogenital tracts of animals, but also, opportunistic pathogens. T. pyogenes causes a variety of purulent infections, such as metritis, mastitis, pneumonia, and abscesses, which, in livestock breeding, generate significant economic losses. Although this species has been known for a long time, many questions concerning the mechanisms of infection pathogenesis, as well as reservoirs and routes of transmission of bacteria, remain poorly understood. Pyolysin is a major known virulence factor of T. pyogenes that belongs to the family of cholesterol-dependent cytolysins. Its cytolytic activity is associated with transmembrane pore formation. Other putative virulence factors, including neuraminidases, extracellular matrix-binding proteins, fimbriae, and biofilm formation ability, contribute to the adhesion and colonization of the host tissues. However, data about the pathogen–host interactions that may be involved in the development of T. pyogenes infection are still limited. The aim of this review is to present the current knowledge about the pathogenic potential and virulence of T. pyogenes.

show abstract

Section: Pathogenesis Of T Pyogenes Infectionmentioning

confidence: 99%

Section: T Pyogenes Genomementioning

confidence: 99%

Pathogenicity and Virulence of Trueperella pyogenes: A Review

Rzewuska

Kwiecień

Chrobak-Chmiel

et al. 2019

IJMS

127

110

View full text Add to dashboard Cite

show abstract

“…The PCR amplification system was the same as that used for the PCR of class 1 integron. The sequences were compared with the sequence of 2012CQ-ZSH [ 22 ]. Sequence analysis was performed using Molecular Evolutionary Genetics Analysis Version 6.0 (MEGA 6.0) software.…”

mentioning

confidence: 99%

Aminoglycoside resistance of <i>Trueperella pyogenes</i> isolated from pigs in China

Dong

Kong

et al. 2017

The Journal of Veterinary Medical Science

View full text Add to dashboard Cite

We aimed to determine the resistance mechanisms of 27 T. pyogenes isolates from swine in the Jilin province of China. Drug sensitivity analysis indicated that most of the isolated strains were resistant to aminoglycosides. We investigated the genes involved in target alteration, drug inactivation, and increased efflux as potential resistance mechanisms. Two known aminoglycoside resistance genes (aphA1 and strB) were not found in the genomic DNA of any isolate. A 3-bp (CCC) deletion in one 16S rRNA operon was detected in all isolates, and efflux pumps were not active in the resistant group. Ultimately, genes encoding aminoglycoside-modifying enzymes carried by class 1 integrons were identified as the main cause of resistance to aminoglycosides in T. pyogenes.

show abstract

“…They found several virulence factors such as collagen adhesion, fimbrial proteins, pyolysin and cytotoxin in the isolate [ 25 ]. Zhang et al [ 26 ] also isolated and sequenced the complete genome of T. pyogenes from livestock and they detected different virulence factor encoding genes including pyolysin, cbpA , fimC , nanH , nanP and fimE genes. However, this is the first study reported the complete genome sequence of T. pyogenes isolated from Water Buffalo ( Bubalus bubalis ) (Table 1 ).…”

Section: Data Descriptionmentioning

confidence: 99%

Complete genome sequence of Trueperella pyogenes strain Arash114, isolated from the uterus of a water buffalo (Bubalus bubalis) in Iran

et al. 2021

View full text Add to dashboard Cite

Objective Trueperella pyogenes has been considered a major causative agent of metritis, abortion, and death in a broad range of domestic and wild animals, including cattle, swine, sheep, goats, camels, buffalo, deer, antelopes, reptiles, and birds. Data description Here, we report the complete chromosome sequence of Trueperella pyogenes strain Arash114, isolated from the uterus of a water buffalo (Bubalus bubalis) died due to the infection caused by this pathogen. The genome assembly comprised 2,338,282 bp, with a 59.5% GC content. Annotation of the genome showed 46 tRNA genes, 6 rRNA, 1 CRISPR and 2059 coding sequences. Also, several genes coding for antimicrobial resistance such as tetW and virulence factor including plo, nanH, nanP, cbp and 4 fimbrial proteins were found. This study will advance our knowledge regarding the metabolism, virulence factors, antibiotic resistance and evolution of Arash114 strain and serve as an appropriate template for future researches.

show abstract

Complete Genome Sequence of Trueperella pyogenes, Isolated from Infected Farmland Goats

Cited by 5 publications

References 12 publications

Pathogenicity and Virulence of Trueperella pyogenes: A Review

Pathogenicity and Virulence of Trueperella pyogenes: A Review

Aminoglycoside resistance of <i>Trueperella pyogenes</i> isolated from pigs in China

Complete genome sequence of Trueperella pyogenes strain Arash114, isolated from the uterus of a water buffalo (Bubalus bubalis) in Iran

Contact Info

Product

Resources

About