Complete regression of a melanocytic nevus after epilation with diode laser therapy

Boleira, Manuela; Lk, de Almeida Balassiano; Jeunon, Thiago

doi:10.5826/dpc.0502a20

Cited by 11 publications

(19 citation statements)

References 14 publications

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“…They also showed that grayish area or milky red veil reflects collagen degeneration on the upper dermis that is the result of inflammatory reaction caused by acute thermal injury. [7][8][9]11,12 Micro-crust usually appeared a few days after photo-irradiation of pigmented lesions. It is explained by destruction of epidermal melanin containing cells and promotion of a rapid differentiation of keratinocytes that leads to an upward transfer of melanocytes along with necrotic keratinocytes.…”

Section: Discussionmentioning

confidence: 99%

“…Histopathologic or electron microscopy studies showed this homogeneous disorganized pigmentation is compatible with micro‐crust composed of keratinocyte debris and numerous melanosomes. They also showed that grayish area or milky red veil reflects collagen degeneration on the upper dermis that is the result of inflammatory reaction caused by acute thermal injury 7‐9,11,12 …”

Section: Discussionmentioning

confidence: 99%

“…Moreover, some of them reported changes of nevi in patients with personal or family history of dysplastic nevi or malignant melanoma, although histologic changes did not reveal enough evidence for malignant transformation. [6][7][8][9][10][11][12] In addition to these scattered reports, recently Guicciardi et al evaluated clinical and dermoscopic effects of photoepilation on 73 melanocytic nevi in a prospective study. They noted pigmentation changes including complete regression and also progressive growth but not malignant modification.…”

Section: Introductionmentioning

confidence: 99%

“…There are some case reports that show regression or dermoscopic changes in the size, pigmentation, and pattern of melanocytic nevi after photo‐depilation with IPL or laser systems. Moreover, some of them reported changes of nevi in patients with personal or family history of dysplastic nevi or malignant melanoma, although histologic changes did not reveal enough evidence for malignant transformation 6‐12 …”

Section: Introductionmentioning

confidence: 99%

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Dermoscopic changes in melanocytic nevi following hair removal laser: A prospective study

Nasimi

Lajevardi

Mahmoudi

et al. 2021

J of Cosmetic Dermatology

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Background: Changes in the appearance of melanocytic nevi have been increasingly reported following hair removal lasers. This could be a source of anxiety in patients doing cosmetic hair removal lasers. Moreover, taking biopsy of any changed nevus following laser is not routinely practical. Therefore, this study was designed to describe dermoscopic changes happened on acquired junctional melanocytic nevi after photodepilation methods. Method:In this prospective study, 66 melanocytic nevi in 27 patients were chosen.Dermoscopic images were taken at the baseline visit and 2 months following single session of hair removal laser. Afterward, the before and after laser images were compared for any change in the structure and color of the nevi.Results: Dermoscopic images showed alterations in nevi following laser including changes in size in 33%, color in 63.6%, newly developed asymmetry in 12.1%, and regression in 3% of nevi. Besides, alteration in reticular and dots and globules pattern was found in 92.5% and 69.32%, respectively. Conclusions:Hair removal laser could induce considerable changes in appearance of acquired junctional melanocytic nevi. Dermoscopic study before and after the process could help to avoid unnecessary excision of suspected lesions.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Dermoscopic changes in melanocytic nevi following hair removal laser: A prospective study

Nasimi

Lajevardi

Mahmoudi

et al. 2021

J of Cosmetic Dermatology

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“…Cases of clinical and corresponding dermoscopic as well as histologic changes were noted to present as early as 15 days after treatment and some had persistent or progressive changes at the last time of follow up, as far as 3 years postexposure. 10,15 Commonly reported changes in studies include complete or partial regression, decreased size, laser induced asymmetry, bleaching, darkening, and altered pattern on dermoscopy, namely changes to the reticular or dot globule pattern. 16,17 Regression, asymmetry, gray areas, and loss of pigment network were alterations reported in multiple cases.…”

Section: Resultsmentioning

confidence: 99%

Changes in melanocytic nevi treated with laser hair removal: A systematic review

2023

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BackgroundIncidental treatment of melanocytic nevi during laser hair removal (LHR) has been noted to cause clinical and dermoscopic changes that may appear similar to findings seen in atypical or neoplastic melanocytic lesions. The rate and characteristics of these changes has not been well‐studied.ObjectivesThe objective of this review article is to assess the literature for reported changes in melanocytic nevi following LHR to guide clinical practice.MethodsPubMed was searched December 5, 2022 for articles evaluating changes in melanocytic nevi after LHR treatment using the following search terms: “nevi laser hair removal,” “nevi diode,” “nevi long pulse alexandrite,” “nevi long pulse neodymium doped yttrium aluminum garnet,” and “melanoma laser hair removal.” All English language patient‐based reports discussing incidental treatment of melanocytic nevi while undergoing LHR with a laser were eligible for inclusion, while reports of changes following hair removal with non‐laser devices such as intense pulsed light were excluded. Studies evaluating non‐melanocytic nevi such as Becker's nevus or nevus of Ota were excluded as were those evaluating the intentional ablation or removal of melanocytic lesions.ResultsTen relevant studies were included, consisting of seven case reports or series and three observational trials, two of which were prospective and one retrospective. Among the seven case reports or series there were a total of 11 patients, six of which had multiple affected nevi. Clinical and dermoscopic changes to nevi following LHR appear to be common in clinical practice, though not well studied. Clinical and dermoscopic changes have been noted to present as early as 15 days after treatment and persist to the maximum time of follow up at 3 years. Commonly reported changes include regression, decreased size, laser induced asymmetry, bleaching, darkening, and altered pattern on dermoscopy. Histologic changes include mild atypia, thermal damage, scar formation, and regression. Although some of the clinical and dermoscopic alterations may be concerning for malignancy, to our knowledge, there are no documented cases of malignant transformation of nevi following treatment with LHR.LimitationsThis study is limited by the low number of relevant reports and their generally small sample size, many of which is limited to single cases. Additionally, comparison of available data was limited by variable reporting of treatment regimens and outcomes.ConclusionsChanges to nevi treated during LHR are not uncommon. Modifications to nevi may occur and look similar to changes seen in dysplastic or neoplastic melanocytic lesions. Notably, despite the widespread use of LHR since the first device was Food and Drug Administration approved in 1995, a time span of nearly three decades, there have been no reported cases of melanoma or severe dysplastic changes within treated nevi. However, dermatologists should be aware that morphologic and dermoscopic alterations can occur after LHR to prevent unnecessary surgical procedures. Although melanoma has not been reported to occur in nevi treated with LHR nor with any other laser exposures, further long‐term data is needed to fully elucidate this concern. Optimally, nevi should be examined by a dermatologist before LHR to determine a baseline clinical and dermoscopic morphology. If there is concern for potential atypia, laser should be avoided over such nevi to avoid confusion at future follow up visits.

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Clinical and dermoscopic evaluation of melanocytic nevi changes during diode laser hair removal: A prospective study

et al. 2022

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Background Laser hair removal (LHR) is a common practice with increasing use worldwide. Clinical and dermoscopic changes in melanocytic nevi after LHR have been reported but prospective studies are lacking. Objective To describe dermoscopic changes of melanocytic nevi at different time points after LHR. Methods Prospective study in a cohort of female patients undergoing diode LHR. Dermoscopic follow‐up of at least three nevi on the legs that underwent hair removal. We included three nonexposed nevi on the arms as controls. Two blinded investigators analyzed dermoscopic images, according to variables selected based on the available literature. Results Thirty‐four patients were included with a total of 148 nevi on the legs and 112 nevi on the arms (controls). 47.9% (71/148) of the nevi on the legs had evidence of dermoscopic changes at the sixth hair removal session, compared to 9.8% (11/112) on controls (p < 0.001). The most frequent change was “bleaching” (41.9%, 62/148). Also, we observed “irregular hyperpigmented areas,” and “regression structures” in 5.4% (8/148) and 4.7% (7/148) of the cases at the sixth session, respectively. Neither of these structures were observed in the controls (p < 0.05). Limitations Only females were included; we did not perform histopathological evaluation nor reflectance confocal microscopy of changing nevi. Conclusion Melanocytic nevi frequently change after diode LHR. The changes cannot always distinguish between LHR induced and melanoma, so we advise avoiding nevi during laser therapies with melanin targets.

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Complete regression of a melanocytic nevus after epilation with diode laser therapy

Cited by 11 publications

References 14 publications

Dermoscopic changes in melanocytic nevi following hair removal laser: A prospective study

Dermoscopic changes in melanocytic nevi following hair removal laser: A prospective study

Changes in melanocytic nevi treated with laser hair removal: A systematic review

Clinical and dermoscopic evaluation of melanocytic nevi changes during diode laser hair removal: A prospective study

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