2020
DOI: 10.3389/fneur.2020.550982
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“Complex” Vasovagal Syncope: A Zebra Among Horses

Abstract: Background: Vasovagal syncope (VVS) occurs due to cerebral hypoperfusion from a fall in blood pressure, with accompanying bradycardia in most cases. Seizure and/or asystole may accompany VVS, though their prediction within the VVS cohort remains elusive.Objective: To further characterize VVS and to find predictive features of “complex” VVS (defined as VVS associated with seizures and/or asystole).Methods: We reviewed medical records of all patients who were referred for orthostatic intolerance and had a defini… Show more

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“…HUTT of these patients become negative after treatment (5). The mechanism of seizure-like activities during HUTT-induced syncope in patients with VVS is due to cerebral ischemia, which is secondary to hypotension, bradycardia, or both (13). Cerebral ischemia inhibits telencephalon and other cortical structures, leading to activation of the subcortical structures, especially the brainstem reticular formation, then convulsion develops (14).…”
Section: Discussionmentioning
confidence: 99%
“…HUTT of these patients become negative after treatment (5). The mechanism of seizure-like activities during HUTT-induced syncope in patients with VVS is due to cerebral ischemia, which is secondary to hypotension, bradycardia, or both (13). Cerebral ischemia inhibits telencephalon and other cortical structures, leading to activation of the subcortical structures, especially the brainstem reticular formation, then convulsion develops (14).…”
Section: Discussionmentioning
confidence: 99%