Complexation of pectin with macro- and microelements. Antianemic activity of Na, Fe and Na, Ca, Fe complexes

Theophylline‐loaded pectin‐based hydrogels. I. Effect of medium pH and preparation conditions on drug release profile

“…Since pectin is versatile material for biomedical applications, nowadays, a number of researchers have been focused on increasing the usage of pectin‐based materials. In literature, some pectin‐based products such as polymer hydrogels, films, nanoparticles, tablets, microspheres, and scaffolds have been synthesized for biomedical applications, and their biological effects have been under investigation . Since pectin is highly hydrophilic, depending on the application area it has been used after treatment, which is a chemically modified pectin [poly(vinyl acetate) grafted pectin etc.…”

Synthesis, Physicochemical Properties and Anti‐Fatigue Effect of Magnesium, Zinc and Chromium Polygalacturonate Based Composition

“…Synthesis of pectin metal complexes (NaMg‐PG, NaZn‐PG and NaCr‐PG) was performed according to the method that was similar to the described by the authors in previous publications,,, wherein water soluble Na, Ca and Fe containing polygalacturonates were used as hematopoiesis stimulators.…”

“…Thus, pectin polysaccharides have a high potential as a unique biologically active matrix for macro and microelements transport into cells at different forms of microelementosis, which opens prospects for new pectin‐based drugs development. In particular, the authors showed earlier that the pectin complex with potassium, iron and calcium ions could be potentially used for iron deficiency anemia treatment ,. Complexation was established to increase therapeutic activity, reduce toxicity, condition specific therapeutic effect and immunological activity of preparations based on pectin polysaccharides ,…”

Synthesis of the new sodium pectinate metal complexes with cobalt and nickel ions and their antimicrobial activity

“…В продолжение исследований комплексообразования пектиновых биополимеров с макро-и микроэлементами [4,5] в настоящей работе взаимодействием пектината натрия (степень солеобразования 35%) получены новые водорастворимые металлокомплексы (рис. 1) натрий-, кобальт-пектинат (ПNaCo) и натрий-, никель-пектинат (ПNaNi) -соединения, проявившие антимикробную активность, что обусловливает расширение спектра их применения.…”

“…Благодаря комплексообразующей способности пектины широко используются в лечебно-профилактических целях в качестве детоксикантов и радиопротекторов [1][2][3]. Кроме того, они перспективны также в качестве органической матрицы для введения в организм необходимых микро-и макроэлементов при различных формах микроэлементозов [4,5].…”