Compliance Barriers in Glaucoma: A Systematic Classification

Tsai, James C.; McClure, Cori A; Ramos, Sarah E; Schlundt, David G.; Pichert, James W.

doi:10.1097/00061198-200310000-00001

Cited by 364 publications

(279 citation statements)

References 14 publications

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“…Both travoprost and timolol are available in BAK-free formulations in some parts of the world (travoprost Z (Alcon Laboratories) and timolol maleate in preservative-free single-dose vials by various manufacturers); however, a multi-bottle regimen is more complex and less convenient than fixed combination therapy, and may be associated with reduced therapeutic compliance. 33 Thus, there is a need for a BAK-free fixed combination IOP-lowering product so that patients requiring more than a single agent for IOP control can be managed medically without chronic exposure to BAK.…”

Section: Discussionmentioning

confidence: 99%

Travoprost 0.004%/timolol 0.5%-fixed combination with and without benzalkonium chloride: a prospective, randomized, doubled-masked comparison of safety and efficacy

Kitazawa

Smith

Sasaki

et al. 2011

Eye

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Section: Discussionmentioning

confidence: 99%

Travoprost 0.004%/timolol 0.5%-fixed combination with and without benzalkonium chloride: a prospective, randomized, doubled-masked comparison of safety and efficacy

Kitazawa

Smith

Sasaki

et al. 2011

Eye

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“…23 We modified the scale to be appropriate for glaucoma patients and eye drop use with input from four practicing ophthalmologists, 10 glaucoma patients taking glaucoma eye drops, the peer-reviewed literature, and results from our earlier work, 31 in which we asked over 300 glaucoma patients from four practices about their problems and concerns in using their glaucoma medications. [32][33][34][35] The main changes that were made to the medication self-efficacy scale in hypertensive patients scale were that the questions asking about specific side effects to anti-hypertensive medications were modified to reflect specific side effects of glaucoma medications. Also, we added a series of questions focusing on ability to use eye drops correctly.…”

Section: Questionnaire Developmentmentioning

confidence: 99%

Development of an instrument to measure glaucoma medication self-efficacy and outcome expectations

Sleath

Blalock

Robin

et al. 2009

Eye

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Purpose The purpose of this study was to develop and evaluate the psychometric properties of (a) a glaucoma medication selfefficacy scale and (b) a glaucoma outcome expectations scale.Patients and Methods Two instruments were developed: a glaucoma medication selfefficacy scale and a glaucoma outcome expectations scale. Packets containing (a) the instruments and patient demographic questions and (b) a letter explaining the study were distributed to 225 glaucoma patients from three ophthalmology practices between August and December 2007. The instrument was completed by 191 patients for a response rate of 85%. Principal components factor analysis with a varimax rotation and Cronbach's a reliability were used to analyse the data. To assess discriminant validity, we administered the scales and two self-reported measures of adherence in a separate sample of 43 glaucoma patients who were currently using at least one glaucoma medication.Results Our results yielded a 21-item self-efficacy in overcoming barriers that might interfere with the use of glaucoma medications scale, a 14-item self-efficacy in carrying out specific tasks required to use eye drops correctly scale, and a four-item glaucoma outcome expectations scale. Results of the Cronbach's a reliability indicated that the scales are internally consistent. The selfefficacy scales were both significantly associated with two patient self-reported measures of glaucoma medication adherence, which show discriminant validity.Conclusions Eye care providers and researchers can use these scales to identify patients with low self-efficacy in using their glaucoma medications and patients who do not believe that following their eye care providers' advice can help their vision.

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“…For some patients this includes multiple medications instilled several times per day. Previous studies have shown that patients commonly miss eye drop doses [1][2][3][4][5][6] and that poor adherence is associated with more severe visual field loss. 7 Kass et al, 1 using an electronic dose monitor, found that 62% of patients omitted 10% of doses and 15% of patients omitted 50% of doses.…”

Section: Introductionmentioning

confidence: 99%

Eye drop instillation technique in patients with glaucoma

Tatham

Sarodia

Gatrad

et al. 2013

Eye

101

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Aims To evaluate the technique of eye drop instillation in patients with glaucoma and assess factors associated with a good technique. Methods A cross-sectional observational study of 85 participants using selfadministered topical medication for glaucoma or ocular hypertension. Patients were asked to demonstrate how they normally instil eye drops using a 5-ml bottle of sterile artificial tear solution. The procedure was recorded and assessed by two masked graders. Whether the patient had been previously shown how to instil drops, the number of eye medications used, and self-perceived difficulty of using drops were also recorded. Conclusions Education relating to eye drop instillation technique is significantly associated with a patient's ability to instil drops correctly. The assessment of a patient's ability to instil eye drops correctly should be a routine part of the glaucoma examination.

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Compliance Barriers in Glaucoma: A Systematic Classification

Cited by 364 publications

References 14 publications

Travoprost 0.004%/timolol 0.5%-fixed combination with and without benzalkonium chloride: a prospective, randomized, doubled-masked comparison of safety and efficacy

Travoprost 0.004%/timolol 0.5%-fixed combination with and without benzalkonium chloride: a prospective, randomized, doubled-masked comparison of safety and efficacy

Development of an instrument to measure glaucoma medication self-efficacy and outcome expectations

Eye drop instillation technique in patients with glaucoma

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