Composição química, atividade bactericida e antioxidante dos óleos essenciais das folhas de Ocimum basilicum e Ocimum gratissimum (Lamiaceae)

Vasconcelos, Sarah Carvalho; Régis, Lauana Alves; Filho, Antônio Carlos Pereira de Menezes; Cazal, Cristiane de Melo; Pereira, Paulo Sérgio; Christofoli, Marcela

doi:10.33448/rsd-v10i8.17109

Cited by 3 publications

(6 citation statements)

References 42 publications

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“…Antimicrobial, insecticidal, antioxidant, antifungal, analgesic, and immunostimulant potentials have also been observed in studies conducted with the species Ocimum gratissimum L. (alfavaca) and Ocimum basilicum (basil) (Vasconcelos et al, 2021).…”

Section: Bioactivity Of Essential Oilsmentioning

confidence: 78%

“…In this sense, the study by Vasconcelos et al (2021) showed that essential oils of O. gratissimum and O. basilicum showed good antioxidant activity in the sequestration of the DPPH free radical and bactericidal activity against strains of E. coli and S. aureus, with the essential oil of O. gratissimum showing greater inhibitory potential than the essential oil of O. basilicum, at the concentrations evaluated.…”

Section: Bioactivity Of Essential Oilsmentioning

confidence: 89%

“…They found that by having a diversity of special metabolites, such as tannins, phenols and flavonoids, these plants demonstrate a variety of biological activities such as antibacterial, antifungal, antiviral, urease inhibitor, antihypertensive, antidiarrheal activities, antiulcerous, anti-inflammatory and biopesticides (Menezes et al, 2020a;Menezes Filho et al, 2021a;Vasconcelos et al, 2021). Among the species evidenced in the study is Mentha arvensis, which has a great reserve of menthol and a wide variety of biological properties such as antispasmodic, antiulcerous, carminative and antimicrobial, because of this its extract and EO has utilities in the cosmeceuticals and pharmaceutical industry.…”

Section: Biological Activity Of Essential Oils In a Health Contextmentioning

confidence: 99%

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Herbal oils in healthcare: a review

Silva

Dotto²

2022

Braz. J. of Sci.

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The herbal medicine market has grown considerably as an alternative currently used for the application of plants in the treatment of various diseases. In this environment, studies on the bioactivity of essential oils and the search for those that have antimicrobial, analgesic, anti-inflammatory, anti-tumor, antioxidant properties and also oils that can inhibit key enzymes are highlighted. However, research on the use of plants in the pharmaceutical industry, chemical composition of native species and possible biological activities are still scarce. Therefore, studies for the knowledge of native species with therapeutic potential gain great relevance. This study carried out a review of the research already done on essential oils from species with potentially promising biological activities for the contribution of the sustainable use of biodiversity and the relevance of their medicinal potential.

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Section: Bioactivity Of Essential Oilsmentioning

confidence: 78%

Section: Bioactivity Of Essential Oilsmentioning

confidence: 89%

Section: Biological Activity Of Essential Oils In a Health Contextmentioning

confidence: 99%

See 1 more Smart Citation

Herbal oils in healthcare: a review

Silva

Dotto²

2022

Braz. J. of Sci.

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“…It is used as a condiment in cooking and as a sedative and anxiolytic, and in traditional medicines for headache and abdominal pain, cough, cold, and bronchitis (Silva et al, 2015a;Ashokkumar et al, 2020). Its essential oil has been used as an anesthetic (Silva et al, 2012;Silva et al, 2015a), antinociceptive (Rabelo et al, 2003;Sahouo et al, 2003;Paula-Freire et al, 2013), anti-inflammatory (Sahouo et al, 2003), antioxidant (Pereira and Maia, 2007;Vasconcelos et al, 2021), insecticide (Nguemtchouin et al, 2013), and antimicrobial against bacteria and fungi (Vasconcelos et al, 2021;Franco et al, 2007;Matasyoh et al, 2007;Adjou et al, 2013;Dambolena et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

“…The essential oil of O. gratissimum (EOGT) is composed of eugenol as a major constituent (Ashokkumar et al, 2020;Vasconcelos et al, 2021;Matasyoh et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of antibiotic efficacy of Ocimum gratissimum L. essential oil against Staphylococcus aureus and Pseudomonas aeruginosa

Leonardo¹,

Flávia²,

Celia³

et al. 2023

J. Med. Plants Res.

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Ocimum gratissimum essential oil (EOGT) has been evaluated for its antibacterial efficacy, and its combinational therapy with antibiotics may enhance the therapeutic efficiency against infectioncausing bacteria. Herein, we evaluated the chemical composition of EOGT and its antibiotic efficacy against Staphylococcus aureus and Pseudomonas aeruginosa. GC-MS and GC-FID analyzed EOGT. The antibiotic efficacy was determined by the agar diffusion method, microdilution, minimum inhibitory concentration (MIC), and fractional inhibitory concentration index (FICI). Eugenol (74.2%) was the main component of OGT. Using the agar diffusion method, the action of rifampicin, ciprofloxacin, and tetracycline was evaluated against S. aureus, while the action of cefepime and ciprofloxacin was evaluated against P. aeruginosa. FICI showed a reduced MIC of ciprofloxacin and tetracycline associated with EOGT. In the presence of EOGT, MIC of ciprofloxacin reduced from 0.6 to 0.0006 μg/mL and of tetracycline decreased from 0.028 to 0.0018 μg/mL against S. aureus and from 4 to 0.12 μg/mL against P. aeruginosa. EOGT enhanced the antibacterial efficacy of the antibiotics suggesting a synergistic effect, thereby enhancing the efficacy in treating infection against S. aureus and P. aeruginosa.

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Evaluation of larvicidal activity of Ocimum basilicum L. essential oil on Aedes (Stegomyia) aegypti L.

Santos,

Monteiro,

Matos

et al. 2024

Cad. Pedagógico

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Aedes aegypti is a mosquito species of significant importance to public health because of its role in the spread of infections in tropical and subtropical regions worldwide. Chemical control measures are crucial for insect management. However, the widespread use of commercial insecticides has led to the development of resistance to Ae. aegypti. Therefore, alternative control measures must be explored. This study aimed to investigate the larvicidal activity and mechanism of action of Ocimum basilicum essential oil against Aedes (Stegomyia) aegypti L. The phytochemical components of the oil were identified using gas chromatography coupled with mass spectrometry analysis, which revealed that oxygenated monoterpenes, primarily Linalool and Estragole, were the major components. The essential oil demonstrated concentration-dependent larvicidal activity, with increased mortality rates at higher concentrations. The larvicidal activity of the essential oil may be enhanced, as shown by molecular docking of its phytochemical components, either individually or in combination with juvenile hormones. These findings suggest that the essential oil has the potential to be used as a larvicide for the management of Ae. aegypti populations and that the mechanism of action may involve interactions between the phytochemical components and juvenile hormones.

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Composição química, atividade bactericida e antioxidante dos óleos essenciais das folhas de Ocimum basilicum e Ocimum gratissimum (Lamiaceae)

Cited by 3 publications

References 42 publications

Herbal oils in healthcare: a review

Herbal oils in healthcare: a review

Evaluation of antibiotic efficacy of Ocimum gratissimum L. essential oil against Staphylococcus aureus and Pseudomonas aeruginosa

Evaluation of larvicidal activity of Ocimum basilicum L. essential oil on Aedes (Stegomyia) aegypti L.

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