Composite Lymphomas and the Relationship of Hodgkin Lymphoma to Non-Hodgkin Lymphomas

Diagnosis of classic Hodgkin lymphoma on bone marrow biopsy

“…The patient refused treatment and died shortly thereafter. The simultaneous occurrence of bone marrow involvement by cHL and non‐Hodgkin lymphoma (NHL) – true composite lymphoma – is rare, and the most common associations are with B cell lymphomas, such as chronic lymphocytic leukaemia (CLL), follicular lymphoma (FL), diffuse large B cell lymphoma (DLBCL) or grey zone lymphomas 22 . Interestingly, some studies have shown a clonal relation between concomitant or subsequent cHL and B‐NHL, especially with Richter transformation of CLL 23,24 .…”