Composition and structure of calcium aluminosilicate microspheres

Sharonova, O. M.; Oreshkina, Natalia A.; Жижаев, А. М.

doi:10.1134/s0040601517060064

Cited by 1 publication

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“…FE-SEM images ( Figure 3 ) depict the surface morphology differences between the three sample types. The white deposits present on the surface of PM are likely the result of calcium deposits [ 30 , 31 ]. Comparing the microspheres, PM appeared to be less round than EGM most likely due to the loss of integrity during sample preparation (also reflecting the low stability).…”

Section: Resultsmentioning

confidence: 99%

Development of Gelatin-Coated Hydrogel Microspheres for Novel Bioink Design: A Crosslinker Study

et al. 2022

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The development of vascularized tissue is a substantial challenge within the field of tissue engineering and regenerative medicine. Studies have shown that positively-charged microspheres exhibit dual-functions: (1) facilitation of vascularization and (2) controlled release of bioactive compounds. In this study, gelatin-coated microspheres were produced and processed with either EDC or transglutaminase, two crosslinkers. The results indicated that the processing stages did not significantly impact the size of the microspheres. EDC and transglutaminase had different effects on surface morphology and microsphere stability in a simulated colonic environment. Incorporation of EGM and TGM into bioink did not negatively impact bioprintability (as indicated by density and kinematic viscosity), and the microspheres had a uniform distribution within the scaffold. These microspheres show great potential for tissue engineering applications.

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Section: Resultsmentioning

confidence: 99%