Composition, isolation, purification and biological activities of Sargassum fusiforme polysaccharides: A review

Zhang, Rui; Zhang, Xinxin; Tang, Yunlian; Mao, Jinlong

doi:10.1016/j.carbpol.2019.115381

Cited by 216 publications

(136 citation statements)

References 37 publications

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“…The reaction mechanism for AuNPs using polysaccharides such as the present using the Ssp is shown in Figure 5c. As described elsewhere [13], there are two major polysaccharide constituents: alginate which is the calcium, sodium or magnesium salt from alginic acid which is composed of (1→4)-α-L-guluronate and β-D-mannuronate residues and fucoidan formed mainly by (1→3)-α-fucose with sulphate groups on some residues at position 4. The reductor character from both compounds is given by their functional groups end, for alginate a carboxylate ion (-COO − ) after salts dissociate in the aqueous media, and for fucoidan from the sulphate group.…”

Section: Characterization Of Gold Nanoparticlesmentioning

confidence: 99%

“…In recent years there has been great interest in the use of Sargassum sp. from the Mexican Caribbean coast, because since mid-2014 there has been an abnormal influx of it, year after year, causing problems related to health, ecosystems, and socioeconomic issues [13,14]. The bioactive components derived from seaweeds, such as polysaccharides, pyropheophytin, tripeptides, phlorotannin, dioxynodehydroeckol, astaxanthin, flavonoids, terpenoids, phenols, and fucoxanthin are shown to have significant antioxidant properties, necessary for the synthesis of metallic nanoparticles [15,16].…”

Section: Introductionmentioning

confidence: 99%

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Developing a CNT-SPE Sensing Platform Based on Green Synthesized AuNPs, Using Sargassum sp.

González-Fuentes

Molina

Silva

et al. 2020

Sensors

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Detection and quantification of diverse analytes such as molecules, cells receptor and even particles and nanoparticles, play an important role in biomedical research, particularly in electrochemical sensing platform technologies. In this study, gold nanoparticles (AuNPs) prepared by green synthesis from Sargassum sp. were characterized using ultraviolet-visible (UV-Vis) and Fourier transform-infrared (FT-IR) spectroscopies, X-ray diffraction (XRD), scanning electron microscopy (SEM), dynamic light scattering (DLS) and zeta potential (ζ) obtaining organic capped face-centered cubic 80–100 nm AuNPs with an excellent stability in a wide range of pH. The AuNPs were used to modify a carbon nanotubes-screen printed electrode (CNT-SPE), through the drop-casting method, to assemble a novel portable electrochemical sensing platform for glucose, using a novel combination of components, which together have not been employed. The ability to sense and measure glucose was demonstrated, and its electrochemical fundamentals was studied using cyclic voltammetry (CV). The limits of detection (LOD) and quantification (LOQ) to glucose were 50 μM and 98 μM, respectively, and these were compared to those of other sensing platforms.

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Section: Characterization Of Gold Nanoparticlesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Developing a CNT-SPE Sensing Platform Based on Green Synthesized AuNPs, Using Sargassum sp.

González-Fuentes

Molina

Silva

et al. 2020

Sensors

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“…Additionally, due to the sulfate ester groups, fucoidans are water soluble polysaccharide polymers [80] exhibiting high affinity to other cell wall components, especially polyphenols [81]. Therefore, various and complicated downstream processes are required to remove such extraneous substances before and after precipitation with ethanol or cationic surfactants to obtain high-purity fucoidans [82,83]. The processes always include pre-treatment, extraction and purification stages as shown in Figure 2.…”

Section: Downstream Processesmentioning

confidence: 99%

Fucoidans: Downstream Processes and Recent Applications

Zayed

Ulber

2020

Marine Drugs

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Fucoidans are multifunctional marine macromolecules that are subjected to numerous and various downstream processes during their production. These processes were considered the most important abiotic factors affecting fucoidan chemical skeletons, quality, physicochemical properties, biological properties and industrial applications. Since a universal protocol for fucoidans production has not been established yet, all the currently used processes were presented and justified. The current article complements our previous articles in the fucoidans field, provides an updated overview regarding the different downstream processes, including pre-treatment, extraction, purification and enzymatic modification processes, and shows the recent non-traditional applications of fucoidans in relation to their characters. of 22reproductive, immune and cell-to-cell communicative roles [23]. As recommended by the International Union of Pure and Applied Chemistry (IUPAC), fucoidans is a general term used to describe sulfated L-fucose-based polymers including sulfated fucans cited by the Swedish scholar Kylin, as well as other fucose-rich sulfated heteropolysaccharides [23,28]. Their chemical structures, in terms of monomeric composition and branching, are quite simple in marine invertebrates compared to their analogues in brown algae [13,29].Hundreds of articles have thoroughly discussed and reviewed the biological, pharmacological and pharmaceutical applications of fucoidans [30][31][32][33], including nanomedicine, [34] which has made it a hot topic in the last few decades [35][36][37]. All these studies tried to investigate fucoidans molecular mechanisms in relation to their chemical structure and physicochemical properties. Therefore, different hypotheses were suggested for each activity, such as anti-tumor [31,[38][39][40], anti-coagulant [41,42], anti-viral [43,44] and anti-inflammatory activity [45,46]. These investigations revealed that various factors are relevant, such as molecular weight, sulfation pattern, sulfate content and monomeric composition [47][48][49]. For example, different fractions were produced with different physicochemical properties in our previous experiments; sulfation pattern and sulfate content were highly related to anti-viral and cytotoxic activities against HSV-1 and Caco-2 cell lines, respectively, while molecular weight and sugar composition were potential factors in anti-coagulation activity [41,50]. In addition, degree of purity was reported as an influential factor [32], where co-extracted contaminants (e.g., phlorotannins or polyphenols) could lead to significant interference in anti-oxidant activity and, consequently, cosmetic applications [51,52].Therefore, several key production challenges regarding fucoidans were discussed in our last review article in order to obtain a product that follows the universal good manufactured practice (GMP) guidelines. The article discussed sources of heterogeneity in extracted fucoidans, including the different biotic (e.g., biogenic, geographical and seas...

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“…The macroalga is cultivated in Japan, Korea, and China (Ma et al, 2017). S. fusiforme is a source of bioactive compounds, such as polysaccharides, which have various functions, including antioxidants, anti-aging, memory improvement and immune regulation (Chen et al, 2016;Bogie et al, 2019;Zhang et al, 2020). It is also an essential herb used to disperse phlegm in traditional Chinese medicine (Li and Wei, 2002).…”

Section: Introductionmentioning

confidence: 99%