Comprehensive analysis reveals KLB as a prognostic biomarker in colorectal cancer based on systematic pancancer analysis
Xiaofei Bi,
Wenjin Zhang,
Meimei Shen Shen
et al.
Abstract:Background
The incidence of colorectal cancer, a prevalent digestive system tumor, is increasing. Earlier research has demonstrated the significant impact of β-Klotho(KLB) on the development of metabolic disorders. Nonetheless, the function of KLB in tumors, particularly in colorectal cancer(CRC), remains underresearched.
Methods
By employing databases such as the TCGA, GTEx, Human Protein Atlas, UALCAN, and cBioPortal, we gathered information regarding KLB expression levels, its predictive and diagnostic im… Show more
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