“…20 This information was absent from 64.9% Acute monoarthritis with specific concern for septic arthritis Giant cell arteritis-significant concern for a diagnosis of giant cell arteritis Acute systemic vasculitis-significant concern for acute development of a systematic vasculitis with major organ involvement, eg, acute pulmonary, cardiac, renal, gastrointestinal, or neurological features; cutaneous vasculitis or digital infarcts Acute connective tissue disease-significant concern for acute development of a connective tissue disease with major organ involvement, eg, acute pulmonary, cardiac, renal, hematological, neurological features; cutaneous vasculitis or digital infarcts Significant unexplained constitutional symptoms of either fever >38°C or weight loss >5% in preceding 6 wk, where there is a strong suspicion that it may relate to a connective tissue disease of referrals in a review of referrals to rheumatology services in the United Kingdom. 21 We acknowledge that people stop work for a wide variety of reasons, and whereas this may not be an important distinguishing factor in the determination of early inflammatory arthritis, 22 it is an important domain to gauge the effect of the problem on the individual. The associated definition makes clear that this domain should be scored with reference to the current condition and not preexisting or other factors.…”