Comprehensive assessment of three typical antibiotics on cyanobacteria (Microcystis aeruginosa): The impact and recovery capability

Du, Yingxiang; Wang, Jing; Zhu, Fengyi; Mai, Dina; Xiang, Zhongrun; Chen, Jianqiu; Guo, Ruixin

doi:10.1016/j.ecoenv.2018.05.035

Cited by 40 publications

(18 citation statements)

References 56 publications

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“…Lipid peroxidation occurs during cellular oxidative stress, leading to the generation of malondialdehyde (MDA), a peroxidation product of fatty acids. Table 12 shows that PHRs such as amoxicillin [219,220,221], ciprofloxacin [108,222], enrofloxacin [95,97], norfloxacin [99,219], levofloxacin [102], tetracycline [57], doxycycline [71], chlortetracycline [64], florfenicol [46], thiamphenicol [46], erythromycin [113,222], spiramycin [220], sulfamethoxazole [222], carbamazepine [170] and ethinylestradiol [179] and PCPs such as triclosan [194,195] can cause increases in MDA content in different microalgal strains. The general pattern in mentioned reports is that MDA content increases up to the maximal concentration with the increase in PHRs/PCPs concentrations in the media.…”

Section: Effect Of Pharmaceuticals and Personal Care Products On Mmentioning

confidence: 99%

“…In another report [220], where Microcystis aeruginosa cells were treated with spiramycin, SOD activity increased, but POD and CAT activities decreased. The SOD activity also decreased in Microcystis aeruginosa exposed to norfloxacin [219]. Results for Microcystis aeruginosa exposed to chlortetracycline show that SOD activity can increase [64] or decrease [69].…”

Section: Effect Of Pharmaceuticals and Personal Care Products On Mmentioning

confidence: 99%

“…Results for Microcystis aeruginosa exposed to chlortetracycline show that SOD activity can increase [64] or decrease [69]. Results for another antibiotic also show that SOD activity decreased in Microcystis aeruginosa exposed to amoxicillin [219], but in another report with amoxicillin treatment, all activities (SOD, POD, CAT) increased [220]. Such discrepancies could possibly occur due to several factors, such as different antibiotic concentrations, different exposure time and imbalance in antioxidant activity and ROS production.…”

Section: Effect Of Pharmaceuticals and Personal Care Products On Mmentioning

confidence: 99%

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Effect of PHRs and PCPs on Microalgal Growth, Metabolism and Microalgae-Based Bioremediation Processes: A Review

Miazek

Brożek-Płuska

2019

IJMS

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In this review, the effect of pharmaceuticals (PHRs) and personal care products (PCPs) on microalgal growth and metabolism is reported. Concentrations of various PHRs and PCPs that cause inhibition and toxicity to growths of different microalgal strains are summarized and compared. The effect of PHRs and PCPs on microalgal metabolism (oxidative stress, enzyme activity, pigments, proteins, lipids, carbohydrates, toxins), as well as on the cellular morphology, is discussed. Literature data concerning the removal of PHRs and PCPs from wastewaters by living microalgal cultures, with the emphasis on microalgal growth, are gathered and discussed. The potential of simultaneously bioremediating PHRs/PCPs-containing wastewaters and cultivating microalgae for biomass production in a single process is considered. In the light of reviewed data, the feasibility of post-bioremediation microalgal biomass is discussed in terms of its contamination, biosafety and further usage for production of value-added biomolecules (pigments, lipids, proteins) and biomass as a whole.

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Section: Effect Of Pharmaceuticals and Personal Care Products On Mmentioning

confidence: 99%

Section: Effect Of Pharmaceuticals and Personal Care Products On Mmentioning

confidence: 99%

Section: Effect Of Pharmaceuticals and Personal Care Products On Mmentioning

confidence: 99%

See 1 more Smart Citation

Effect of PHRs and PCPs on Microalgal Growth, Metabolism and Microalgae-Based Bioremediation Processes: A Review

Miazek

Brożek-Płuska

2019

IJMS

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“…The results showed that the biofilm EPS content was increased to cope with the stress of FF and OFL. It was reported that the synthesis and secretion of EPS could be promoted when Microcystis aeruginosa was exposed to the antibiotic norfloxacin [24]. It was necessary to further elucidate the role of EPS components under the antibiotic stress.…”

Section: Resultsmentioning

confidence: 99%

“…Chlorophyll a is well-known as an important property of algae vitality, and is intimately involved in all aspects of primary photosynthesis; its content can be used to estimate the primary productivity [20]. It was found that excessive cellular reactive oxygen species (ROS) produced by antibiotic stress could damage the microbial chloroplast membrane system and the chlorophyll a content of algae decreased under the stress of norfloxacin, amoxicillin, cefradine, streptomycin, and tetracycline [19,21,22,23,24,25]. Antibiotics could also induce oxidative stress and cause antioxidant responses for algae cell to adapt to the changes of the external environment.…”

Section: Introductionmentioning

confidence: 99%

Response of Freshwater Biofilms to Antibiotic Florfenicol and Ofloxacin Stress: Role of Extracellular Polymeric Substances

Wang

Dong

Zhang

et al. 2019

IJERPH

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Antibiotic residues have been detected in aquatic environments worldwide. Biofilms are one of the most successful life forms, and as a result are ubiquitous in natural waters. However, the response mechanism of freshwater biofilms to the stress of various antibiotic residues is still unclear. Here, the stress of veterinary antibiotic florfenicol (FF) and fluoroquinolone antibiotic ofloxacin (OFL) on freshwater biofilms were investigated by determining the changes in the key physicochemical and biological properties of the biofilms. The results showed that the chlorophyll a content in biofilms firstly decreased to 46–71% and then recovered to original content under the stress of FF and OFL with high, mid, and low concentrations. Meanwhile, the activities of antioxidant enzymes, including superoxide dismutase and catalase, increased between 1.3–6.7 times their initial values. FF was more toxic to the biofilms than OFL. The distribution coefficients of FF and OFL binding in extracellular polymeric substances (EPS)-free biofilms were 3.2 and 6.5 times higher than those in intact biofilms, respectively. It indicated that EPS could inhibit the FF and OFL accumulation in biofilm cells. The present study shows that the EPS matrix, as the house of freshwater biofilms, is the primary barrier that resists the stress from antibiotic residues.

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Development and Application of a Microplate Assay for Toxicity Testing on Aquatic Cyanobacteria

Page

Gunnarsson

Snape

et al. 2020

Enviro Toxic and Chemistry

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Regulatory environmental risk assessment, applied to establish a protection limit for all bacterial diversity in surface waters, relies on a growth inhibition test performed on a single species of cyanobacteria and the activated sludge respiration inhibition test. Recently, the ability of this approach to protect adequately for bacteria that provide important ecosystem services has been questioned, and empirical data on additional species to further investigate the effectiveness of the environmental risk assessment are urgently required. We present the development and validation of a cost‐effective and time‐efficient microplate assay that is comparable to the traditional shake flask test for measurement of cyanobacteria growth rate after chemical exposure. The assay has been optimized to ensure that comparisons of cyanobacteria sensitivity under exponential growth are assessed across equivalent experimental conditions using phycocyanin fluorescence as a surrogate for cell density. The test system is validated using potassium dichromate, and the results are compared with those obtained in an Organisation for Economic Co‐operation and Development (2011) test guideline 201 shake flask test system. This assay is suitable for the screening of new and legacy chemicals (including antibiotics) for which ecotoxicology data are lacking across a wide range of cyanobacteria, with the aim of developing more comprehensive environmental risk assessment. Environ Toxicol Chem 2020;39:705–720. © 2019 SETAC

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Comprehensive assessment of three typical antibiotics on cyanobacteria (Microcystis aeruginosa): The impact and recovery capability

Cited by 40 publications

References 56 publications

Effect of PHRs and PCPs on Microalgal Growth, Metabolism and Microalgae-Based Bioremediation Processes: A Review

Effect of PHRs and PCPs on Microalgal Growth, Metabolism and Microalgae-Based Bioremediation Processes: A Review

Response of Freshwater Biofilms to Antibiotic Florfenicol and Ofloxacin Stress: Role of Extracellular Polymeric Substances

Development and Application of a Microplate Assay for Toxicity Testing on Aquatic Cyanobacteria

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