Comprehensive bioinformatics analysis and cell line experiments revealed the important role of CDCA3 in sarcoma

Li, Yang; Wu, Zhiwei; Ding, Tao; Zhang, Wenbiao; Guo, Hongjuan; Huang, Fei

doi:10.1016/j.heliyon.2024.e32785

Heliyon

2024

DOI: 10.1016/j.heliyon.2024.e32785

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Comprehensive bioinformatics analysis and cell line experiments revealed the important role of CDCA3 in sarcoma

Yang Li,

Zhiwei Wu,

Tao Ding

et al.

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Leveraging Nanoengineered Microneedle‐Augmented Drug Delivery in Oncological Intervention

Singh,

Shukla

2024

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The landscape of chemotherapy for cancer is experiencing a dramatic transition with the integration of sophisticated drug delivery methods, especially nanoengineered microneedles. Percutaneous vaccination is regarded the optimum therapeutic approach due to the high amount of immune cell accumulation and the rich capillary lymphatic system in the dermis. The curative impact of Microneedles‐based cancer vaccines is suboptimal due to the complicated mix of tumor, host, and environmental variables, as well as the vaccine's restricted loading capacity. As a result, additional enhancements are still needed to accelerate their clinical translation. This article offers a meticulous analysis of the avant‐garde strategies harnessed to augment drug delivery via microneedle. Various tactics, such as tailored nanoparticle carriers, functionalized microneedle arrays, and real‐time monitoring system, work together to improve therapeutic efficacy and prevent off‐target effects. By integrating recent advancement and delineating future trajectories, this article gives an in‐depth analysis of how nanoengineered microneedle‐augmented technologies have the potential to change the face of cancer therapy, heralding in a new era of precision medicine and better outcomes.

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Leveraging Nanoengineered Microneedle‐Augmented Drug Delivery in Oncological Intervention

Singh,

Shukla

2024

Part & Part Syst Charact

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Comprehensive bioinformatics analysis and cell line experiments revealed the important role of CDCA3 in sarcoma

Cited by 1 publication

References 40 publications

Leveraging Nanoengineered Microneedle‐Augmented Drug Delivery in Oncological Intervention

Leveraging Nanoengineered Microneedle‐Augmented Drug Delivery in Oncological Intervention

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