Comprehensive malnutrition inflammation score as a marker of nutritional status in Chinese peritoneal dialysis patients

Chan, Jessie Ying Wing; I, Kit; Lam, Karry Mau Chu; Chow, Kai‐Ming; Chung, Kwok-Yi; Li, Philip Kam-Tao; Szeto, Cheuk‐Chun

doi:10.1111/j.1440-1797.2006.00693.x

Cited by 27 publications

(27 citation statements)

References 25 publications

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“…The method of dialysis adequacy assessment has been described previously (26). Nutritional status was represented by serum albumin level, subjective global assessment (SGA) (27), and comprehensive malnutrition-inflammation score (MIS) (28), which has been validated in PD patients (29,30 A multiple linear regression model was constructed to determine independent predictors of the slope of residual GFR decline. In addition, we constructed a Cox proportional hazard model to determine independent predictors of time to anuria.…”

Section: Dialysis Adequacy and Nutritional Indicesmentioning

confidence: 99%

Predictors of Residual Renal Function Decline in Patients Undergoing Continuous Ambulatory Peritoneal Dialysis

et al. 2015

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♦ Background: Residual renal function (RRF) is an important prognostic indicator in continuous ambulatory peritoneal dialysis (CAPD) patients. We determined the predictors of RRF loss in a cohort of incident CAPD patients. ♦ Methods: We reviewed the record of 645 incident CAPD patients. RRF loss is represented by the slope of decline of residual glomerular filtration rate (GFR) as well as the time to anuria. ♦ Results: The average rate of residual GFR decline was -0.083 ± 0.094 mL/min/month. The rate of residual GFR decline was faster with a higher proteinuria (r = -0.506, p < 0.0001) and baseline residual GFR (r = -0.560, p < 0.0001). Multivariate analysis showed that proteinuria, baseline residual GFR, and the use of diuretics were independent predictors of residual GFR decline. Cox proportional hazard model showed that proteinuria, glucose exposure, and the number of peritonitis episodes were independent predictors of progression to anuria, while a higher baseline GFR was protective. Each 1 g/day of proteinuria is associated with a 13.2% increase in the risk of progressing to anuria, each 10 g/day higher glucose exposure is associated with a 2.5% increase in risk, while each peritonitis episode confers a 3.8% increase in risk. ♦ Conclusions: Our study shows that factors predicting the loss of residual solute clearance and urine output are different. Proteinuria, baseline residual GFR, and the use of diuretics are independently related to the rate of RRF decline in CAPD patients, while proteinuria, glucose exposure, and the number of peritonitis episodes are independent predictors for the development of anuria. The role of antiproteinuric therapy and measures to prevent peritonitis episodes in the preservation of RRF should be tested in future studies.

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Section: Dialysis Adequacy and Nutritional Indicesmentioning

confidence: 99%

Predictors of Residual Renal Function Decline in Patients Undergoing Continuous Ambulatory Peritoneal Dialysis

et al. 2015

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“…A prevalência de inflamação é descrita em torno de 61,9% na população em DP, mesmo em condições clínicas está-veis 9 . A prevalência de desnutrição varia de 32,9% a 51,2% na forma leve a moderada e de 2,6% a 4,2% para desnutrição grave 1, [10][11][12] . A associação entre inflamação, desnutrição e aterosclerose tem sido relacionada à alta mortalidade por DCV em pacientes portadores de DRC 3,7 .…”

Section: N T R O D U ç ã Ounclassified

“…Contudo os percentuais encontrados foram menores do que os registrados em alguns estudos, nos quais a desnutrição na forma leve a moderada se situa entre 39,2% e 51,2% e na forma grave entre 2,6% a 4,2% 1, [10][11][12] . O nível sérico de albumina neste estudo também se encontrou abaixo do valor recomendado.…”

Section: I S C U S S ã Ounclassified

Desnutrição, inflamação e outros fatores de risco para doença cardiovascular em pacientes sob diálise peritoneal

et al. 2010

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DESNUTRIÇÃO E INFLAMAÇÃO | 335Rev. Nutr., Campinas, 23(3):335-345, maio/jun., 2010Revista R E S U M O ObjetivoIdentificar a ocorrência de desnutrição, inflamação e outros fatores de risco para doença cardiovascular em pacientes sob diálise peritoneal. MétodosEstudo transversal, envolvendo 61 pacientes em duas unidades de diálise em Salvador (BA). O estado nutricional foi avaliado por meio da Avaliação Subjetiva Global. Realizou-se a dosagem de proteína C reativa ultrassensível para determinar inflamação. Foram estudados fatores de risco tradicionais para doença cardiovascular, como gênero, idade, etilismo, tabagismo, sedentarismo, hipertensão, diabetes, dislipidemia e hábitos alimentares e fatores não tradicionais, como alterações no metabolismo de cálcio, fósforo e anemia. ResultadosNessa população, 36,0% dos pacientes encontravam-se desnutridos e 49,2% com processo inflamatório. Desnutrição e inflamação foram evidenciadas em 21,3% dos pacientes. O grupo de pacientes desnutridos

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“…The sum of scores ranges from zero to 30 indicates a normal nutritional status or mild malnutrition; a score of 9-18 indicates moderate malnutrition, and a score greater than 18, severe malnutrition. This score provides a correlation coefficient greater than isolated laboratory values and other scores such as SGA 23,24 .…”

Section: Erythropoietin Resistance Indexmentioning

confidence: 99%

Doses intermitentes de estatina em pacientes em hemodiálise com LDL-colesterol espontaneamente baixo

Suassuna¹,

Bastos²

2008

Arq. Bras. Cardiol.

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SummaryBackground: Mortality in dialysis patients remains high and is due mainly to cardiovascular causes. Inflammation has a role in the genesis of accelerated atherosclerosis, vascular calcification, malnutrition and anemia, and a huge impact on the survival of these patients. The pleiotropic effects of statins can be a therapeutic option for reducing chronic inflammatory processes of patients undergoing hemodialysis.

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Comprehensive malnutrition inflammation score as a marker of nutritional status in Chinese peritoneal dialysis patients

Cited by 27 publications

References 25 publications

Predictors of Residual Renal Function Decline in Patients Undergoing Continuous Ambulatory Peritoneal Dialysis

Predictors of Residual Renal Function Decline in Patients Undergoing Continuous Ambulatory Peritoneal Dialysis

Desnutrição, inflamação e outros fatores de risco para doença cardiovascular em pacientes sob diálise peritoneal

Doses intermitentes de estatina em pacientes em hemodiálise com LDL-colesterol espontaneamente baixo

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