Comprehensive review and updated analysis of DNA methylation in hepatocellular carcinoma: From basic research to clinical application
Lin Su,
Jiawen Bu,
Jiahui Yu
et al.
Abstract:Hepatocellular carcinoma (HCC) is a primary malignant tumour, ranking second in global mortality rates and posing significant health threats. Epigenetic alterations, particularly DNA methylation, have emerged as pivotal factors associated with HCC diagnosis, therapy, prognosis and malignant progression. However, a comprehensive analysis of the DNA methylation mechanism driving HCC progression and its potential as a therapeutic biomarker remains lacking. This review attempts to comprehensively summarise various… Show more
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