Computational fluid dynamics analysis of H-uvulopalatopharyngoplasty in obstructive sleep apnea syndrome

The aim of this study is to evaluate the efficacy of uvulopalatopharyngoplasty and the corresponding postoperative airflow. Eleven patients diagnosed with obstructive sleep apnea syndrome who complained of snoring and apnea were enrolled in this study. Computational fluid dynamics (CFD) was implemented. CFD could be accomplished in nine cases. Airflow analysis was not possible in cases with a high respiratory event index (REI) score. Before surgery, stenosis was identified in the oropharynx and epiglottic area. And the airflow velocity and pressure were found to have significantly decreased in the oropharynx postoperatively, while in the epiglottic area, those data had increased postoperatively in some cases. The velocity and pressure of the oropharynx are related to REI score. From the CFD analysis, airflow analysis is important for evaluating the apnea state. It is suggested that the postoperative function can now be predicted preoperatively.

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“…In terms of the parametric factor for CFD, DP is recommended by some authors [12,15,27]. DP is calculated by a difference of two points.…”

Section: Discussionmentioning

confidence: 99%

“…There have also been some case reports for adults [13,14]. Additionally, one report evaluated airflow for an adult who underwent modified uvulopalatopharyngoplasty (UPPP) [15].…”

Section: Introdcutionmentioning

confidence: 99%

Postoperative functional evaluation of obstructive sleep apnea syndrome by computational fluid dynamics

Nomura

Horikoshi

Kitano

et al. 2021

Indian J Otolaryngol Head Neck Surg

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“…With the development of the biomechanical technique and on the basis of studies on the air ow characteristics in normal airway, there are more and more researches on the internal ow eld of upper airway in OSA patients. In order to meet the needs of clinical diagnosis and treatment, scholars have carried out a lot of CFD studies on the biomechanical model of upper airway in OSA patients, from simulating various virtual surgeries [9] to evaluating the real surgical effects [10][11][12]. Based on the previous studies, CFD has been considered to have high reliability and accuracy, can be used to evaluate the changes of air ow in the upper airway caused by stenosis in OSA patients, also can be used to quantitatively analyze the in uence of the changes caused by surgical treatments on air ow characteristics, which are helpful to objectively evaluate the curative effects after surgical treatment.…”

Section: Discussionmentioning

confidence: 99%

What Is the Impact of Distraction Osteogenesis on the Upper Airway of Hemifacial Microsomia Patient With OSA: a Case Report

Wang

Yang

2021

Preprint

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Background: Current researches about hemifacial microsomia (HFM) patients after distraction osteogenesis (DO) most emphasize the morphologic changes. This case report shows the outcome of DO on the upper airway of a HFM patient with obstructive sleep apnea (OSA) based on the use of computational fluid dynamics (CFD).Case presentation: A boy of 11-year-old was diagnosed as HFM with OSA, and underwent unilateral DO. Polysomnography and CT scans were performed before and six months after treatment. After DO, lowest blood oxygen saturation increased from 81% to 95% and apnea and hypopnea index decreased from 6.4 events/hour to 1.2 events/hour. The oropharynx and nasopharynx were obviously expanded. We observed apparently increased average pressure, decreased average velocity and pressure drop in all cross-sections, and largely decreased airflow resistance and maximum velocity entirely in the airway.Conclusions: The results suggest that DO might be effective for the treament of OSA by expanding the upper airway and reducing the resistance of inspiration.

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“…The upper and lower connecting airways were considered on the respiratory airway tract without omitting it, which extended from the nasal to the terminal bronchioles. Valuable information obtained from the CFD results, such as airflow pattern, can contribute to the baseline data to provide a complete understanding of respiratory physiology [23] and airway collapsibility [113] .…”

Section: Correlationmentioning

confidence: 99%

Computational fluid dynamics modelling of human upper airway: A review

Faizal

Ghazali

Khor

et al. 2020

Computer Methods and Programs in Biomedicine

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Background and objective: Human upper airway (HUA) has been widely investigated by many researchers covering various aspects, such as the effects of geometrical parameters on the pressure, velocity and airflow characteristics. Clinically significant obstruction can develop anywhere throughout the upper airway, leading to asphyxia and death; this is where recognition and treatment are essential and lifesaving. The availability of advanced computer, either hardware or software, and rapid development in numerical method have encouraged researchers to simulate the airflow characteristics and properties of HUA by using various patient conditions at different ranges of geometry and operating conditions. Computational fluid dynamics (CFD) has emerged as an efficient alternative tool to understand the airflow of HUA and in preparing patients to undergo surgery. The main objective of this article is to review the literature that deals with the CFD approach and modeling in analyzing HUA.Methods: This review article discusses the experimental and computational methods in the study of HUA. The discussion includes computational fluid dynamics approach and steps involved in the modeling used to investigate the flow characteristics of HUA. From inception to May 2020, databases of PubMed, Embase, Scopus, the Cochrane Library, BioMed Central, and Web of Science have been utilized to conduct a thorough investigation of the literature. There had been no language restrictions in publication and study design of the database searches. A total of 117 articles relevant to the topic under investigation were thoroughly and critically reviewed to give a clear information about the subject. The article summarizes the review in the form of method of studying the HUA, CFD approach in HUA, and the application of CFD for predicting HUA obstacle, including the type of CFD commercial software are used in this research area.

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Computational fluid dynamics analysis of H-uvulopalatopharyngoplasty in obstructive sleep apnea syndrome

Cited by 10 publications

References 28 publications

Postoperative functional evaluation of obstructive sleep apnea syndrome by computational fluid dynamics

Postoperative functional evaluation of obstructive sleep apnea syndrome by computational fluid dynamics

What Is the Impact of Distraction Osteogenesis on the Upper Airway of Hemifacial Microsomia Patient With OSA: a Case Report

Computational fluid dynamics modelling of human upper airway: A review

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