2022
DOI: 10.21203/rs.3.rs-2310316/v1
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Computational Network Analysis of Host Genetic Risk Variants of Severe COVID-19

Abstract: Background: Genome-wide association studies have identified numerous human host genetic risk variants that play a substantial role in the host immune response to SARS-CoV-2. Although these genetic risk variants significantly increase the severity of COVID-19, their influence on body systems is poorly understood. Therefore, we aim to interpret the biological mechanisms and pathways associated with the genetic risk factors and immune responses in severe COVID-19. We perform a deep analysis of previously identifi… Show more

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