Computational Studies on the Molecular Structure, Vibrational Spectra, Natural Bond Orbital, Molecular Electrostatic Potential and UV-Vis Analyses of (&lt;I&gt;E&lt;/I&gt;)-3-(4-bromophenyl)-1-(3,4-dichlorophenyl)Prop-2-En-1-One

Gupta, Ujval; Mahajan, Surbhi; Singh, Vivek K.; Khajuria, Yugal

doi:10.1166/mat.2014.1198

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Bis-chalcones With Hydrazine Hydrate1

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2022

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“…Bis-chalcones (22) were reacted with hydrazine hydrate in the presence of acetic acid to give bis-3,5-diphenyl pyrazoline (23) (Scheme 9) [79].…”

Section: Bis-chalcones With Hydrazine Hydratementioning

confidence: 99%

“…Recently, several chalcone-based compounds have been approved for clinical use, for example Metochalcone I was once marketed as a choleretic drug, while Sofalcone II was previously used as an antiulcer and nucoprotective drug (Figure 2) [18]. In addition, chalcones and their derivatives have great applications as sweeteners [19,20], fluorescent whitening factor [21], heat maintenance [22], and brightening agent [23].…”

Section: Introductionmentioning

confidence: 99%

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Synthesis, reactions, and applications of chalcones: A review

Morsy

Hassan

2022

Eur J Chem

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Considering the essential biological and medicinal properties of chalcones, the synthesis of these compounds has attracted the interest of medicinal and organic chemists. This review aims to describe the different strategies developed so far for the synthesis of chalcones and their applications. After a brief introduction of the chalcones and their biological activities, different synthetic approaches such as chemical and other methods are described and organized on the basis of the catalysts and the other reagents employed in the syntheses. Some of the reactions have been applied successfully to the synthesis of biologically important compounds. Moreover, the biological and pharmacological activities of chalcones have been shown.

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“…Bis-chalcones (22) were reacted with hydrazine hydrate in the presence of acetic acid to give bis-3,5-diphenyl pyrazoline (23) (Scheme 9) [79].…”

Section: Bis-chalcones With Hydrazine Hydratementioning

confidence: 99%