Computed tomography in the diagnosis of bronchiectasis

Amaral, Ricardo Holderbaum do; Nin, Carlos Schüler; Souza, Vinicius Valerio de; Marchiori, Edson; Hochhegger, Bruno

doi:10.1183/09031936.00031415

Cited by 8 publications

(5 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Bronchiectasis is an anatomical description, referring to abnormal widening of the bronchi which may be caused by a wide range of inherited and acquired disorders [ 1 – 3 ].…”

Section: What Is Bronchiectasis?mentioning

confidence: 99%

See 1 more Smart Citation

Global impact of bronchiectasis and cystic fibrosis

Redondo

Keyt

Dhar

et al. 2016

Breathe

View full text Add to dashboard Cite

Educational aimsTo recognise the clinical and radiological presentation of the spectrum of diseases associated with bronchiectasis.To understand variation in the aetiology, microbiology and burden of bronchiectasis and cystic fibrosis across different global healthcare systems.Bronchiectasis is the term used to refer to dilatation of the bronchi that is usually permanent and is associated with a clinical syndrome of cough, sputum production and recurrent respiratory infections. It can be caused by a range of inherited and acquired disorders, or may be idiopathic in nature. The most well recognised inherited disorder in Western countries is cystic fibrosis (CF), an autosomal recessive condition that leads to progressive bronchiectasis, bacterial infection and premature mortality.Both bronchiectasis due to CF and bronchiectasis due to other conditions are placing an increasing burden on healthcare systems internationally. Treatments for CF are becoming more effective leading to more adult patients with complex healthcare needs. Bronchiectasis not due to CF is becoming increasingly recognised, particularly in the elderly population. Recognition is important and can lead to identification of the underlying cause, appropriate treatment and improved quality of life. The disease is highly diverse in its presentation, requiring all respiratory physicians to have knowledge of the different “bronchiectasis syndromes”. The most common aetiologies and presenting syndromes vary depending on geography, with nontuberculous mycobacterial disease predominating in some parts of North America, post-infectious and idiopathic disease predominating in Western Europe, and post-tuberculosis bronchiectasis dominating in South Asia and Eastern Europe.Ongoing global collaborative studies will greatly advance our understanding of the international impact of bronchiectasis and CF.

show abstract

“…Bronchiectasis is an anatomical description, referring to abnormal widening of the bronchi which may be caused by a wide range of inherited and acquired disorders [ 1 – 3 ].…”

Section: What Is Bronchiectasis?mentioning

confidence: 99%

“…Radiologically, bronchiectasis is most easily identified by computed tomography (CT) [ 3 ]. At any level, the diameter of the bronchi should be less than the adjacent blood vessel (known as the bronchoarterial ratio) [ 4 ].…”

Section: What Is Bronchiectasis?mentioning

confidence: 99%

Global impact of bronchiectasis and cystic fibrosis

Redondo

Keyt

Dhar

et al. 2016

Breathe

View full text Add to dashboard Cite

show abstract

“…The presented patient endure the clinical features of the disease such as sputum production, cough and repeated infections, In addition, CT chest done to the patient showed bilateral septal thickening and ground-glass opacity mild bronchiectasis changes (Figure 1), high resolution CT scan of the chest is considered as the gold standard for confirmation of bronchiectasis [9]. forced vital capacity [FVC], lung function test, sputum bacteriological culture and chest radiograph can also be needed to establish a proper diagnosis [10].Others differential respiratory illnesses such as TB has been laboratory excluded.…”

Section: Discussionmentioning

confidence: 99%

A Sudanese Female Case with Rheumatoid Arthritis and Bronchiectasis as a Presentation and Low Vitamin D Level

Essa¹,

Taha²,

Abdelhalim³

et al. 2021

BJSTR

View full text Add to dashboard Cite

Rheumatoid arthritis (RA) is a common autoimmune multi-systemic inflammatory disease affecting joints result in dysfunction and ultimately damage. Bronchiectasis (BR) is a long-term pulmonary condition that is characterized by permanent dilation of the bronchial, the association of RA and BR has been recognized since the past five decades. This is the first reported document arthropathy in a female patient with bronchiectasis in Sudan. We aim to bring attention to the uncommon presentations and challenge of diagnosing patients of BR with RA. We are presenting 48 years old female complaining of chronic cough, chest pain and multiple joints pain. examination showed Tender joints, Z-shape thumbs appearance figure and hyper flexed DIP deformity in index fingers. chest auscultation reveals bilateral Coarse crackles disappears after coughing. Chest CT scan showed features suggested the diagnosis of BR, Anti-ccp positive, rheumatoid factor IgM, all indicate a diagnosis of RA in addition, the patient has low serum Vitamin D. Patient received hydroxychloroquine, Mycophenolate mofetil, vitamin D and calcium supplements and her general condition is improved.

show abstract

“…The bronchiectasis diagnosis was recorded according to the International Classification of Diseases Clinical Modification code 494.0 or 494.1 (ninth revision) or J47 (tenth revision). The diagnosis of bronchiectasis was confirmed by the interpretation of chest radiography or high-resolution computed tomography (HRCT), which was independently reviewed by a radiologist ( Nicotra et al, 1995 ; Amaral et al, 2015 ). Patients with at least two primary bronchiectasis diagnoses on different dates during outpatient visits or one diagnosis during hospitalization were included in the cohort.…”

Section: Methodsmentioning

confidence: 99%

Impacts of Nontuberculous Mycobacteria Isolates in Non-cystic Fibrosis Bronchiectasis: A 16-Year Cohort Study in Taiwan

et al. 2022

View full text Add to dashboard Cite

BackgroundThe prevalence of nontuberculous mycobacteria (NTM) in patients with chronic respiratory disease has increased. The implication of NTM in non-CF bronchiectasis remained controversial. This study investigated the impact of NTM in non-CF bronchiectasis in Taiwan.MethodsClinical manifestation, imaging, and microbiological data were retrieved from the Chang Gung Research Database, the largest electronic medical record-based database in Taiwan. Patients with bronchiectasis during 2001–2016 were included. Cox proportional hazard model was employed to compare outcomes between patients with negative and positive NTM isolates after 1:1 propensity score matching.ResultsA total of 19,647 non-CF bronchiectasis patients were enrolled and 11,492 patients were eligible for analysis after exclusion screening. Finally, patients with negative and positive NTM isolates—650 each—were analyzed after propensity score matching. The patients with negative NTM isolates were divided into three groups: Pseudomonas aeruginosa isolates (n = 53); fungus isolates (n = 26); and concomitant P. aeruginosa and fungus isolates (n = 8). The patients with positive NTM isolates were divided into five groups: single NTM isolate (n = 458); multiple NTM isolates (n = 60); concomitant NTM and P. aeruginosa isolates (n = 89); concomitant NTM and fungus isolates (n = 33); and concomitant NTM, P. aeruginosa, and fungus isolates (n = 10). Patients with P. aeruginosa isolates; concomitant NTM and P. aeruginosa isolates; concomitant NTM, P. aeruginosa, and fungus isolates had independently associated with respiratory failure and death. Patients with single or multiple NTM isolates were not related to ventilator use, but both were independent risk factor for mortality.ConclusionNTM, either combined with P. aeruginosa or fungus, exhibited more frequent exacerbations in non-CF bronchiectasis patients. Moreover, NTM predicted mortality in non-CF bronchiectasis patients and were also correlated to respiratory failure while concomitantly isolated with P. aeruginosa and fungus.

show abstract

Computed tomography in the diagnosis of bronchiectasis

Cited by 8 publications

References 6 publications

Global impact of bronchiectasis and cystic fibrosis

Global impact of bronchiectasis and cystic fibrosis

A Sudanese Female Case with Rheumatoid Arthritis and Bronchiectasis as a Presentation and Low Vitamin D Level

Impacts of Nontuberculous Mycobacteria Isolates in Non-cystic Fibrosis Bronchiectasis: A 16-Year Cohort Study in Taiwan

Contact Info

Product

Resources

About