Computed Tomography Measured Psoas Cross Sectional Area Is Associated With Bone Mineral Density Measured by Dual Energy X-Ray Absorptiometry

Touban, Basel M.; Sayegh, Michael J.; Galina, Jesse; Pavlesen, Sonja; Radwan, Tariq; Anders, Mark J.

doi:10.1016/j.jocd.2022.04.001

Cited by 10 publications

(4 citation statements)

References 29 publications

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“…Existing research has confirmed that sling core stabilization training outperforms conventional training in increasing the strength and stability of spinal muscle groups [ 15 ]. A study by Touban BM [ 16 ] confirmed that the cross-sectional area of the core muscles of the lumbar abdomen is positively correlated with bone density. As revealed by the analysis of the trend of changes in BMD in this patient, calcium and vitamin D supplementation-based long-term regular sling core stabilization training increased the very cross-sectional area of the core muscles by increasing the very cross-sectional area of the core muscles to improve BMD.…”

Section: Discussionmentioning

confidence: 99%

Regular sling core stabilization training improves bone density based on calcium and vitamin D supplementation

Liu,

Xu,

Liu

et al. 2023

BMC Musculoskelet Disord

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Background Primary osteoporosis refers to a disease of aging characterized by reduced bone mass, damage to bone tissue microarchitecture, and predisposition to fracture.Sling core stabilization training emphasizes activating the deep local muscles of the spine under unstable conditions, and enhancing the body’s balance and control during exercise. Case presentation A 70-year-old female went to the Acupuncture and Rehabilitation Department due to low back pain caused by osteoporosis.The patient received sling core stabilization training three times a week based on Calcium and Vitamin D Supplementation. After training, the patient’s back pain was significantly relieved and insisted one year. In the physical examination of bone mineral density, the results showed that the value of bone mineral density was better than last year.The patients adhered to sling core stabilization training and observed the changes of bone mineral density every year basis on calcium and vitamin D supplementation. Discussion However, cases of calcium and vitamin D supplementation-based regular sling core stabilization training that improves bone density in osteoporosis patients have been rarely reported. Our group shared cases and analyzed possible mechanisms, hoping to provide reference for the prevention and treatment of primary osteoporosis.

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Section: Discussionmentioning

confidence: 99%

Regular sling core stabilization training improves bone density based on calcium and vitamin D supplementation

Liu,

Xu,

Liu

et al. 2023

BMC Musculoskelet Disord

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“…Although DXA is still to be the gold standard in osteoporosis diagnostic programs, several studies have reported the opportunistic role of CT scan as a useful tool for assessing BMD [22] since DXA cannot be used in patients with scoliosis or calcifications from chronic disease, metal implants in both hips or at multiple levels of the spine, or cement in a vertebral body. In addition, DXA cannot distinguish cancellous bone from cortical bone quality as it is based on two dimensions.…”

Section: Discussionmentioning

confidence: 99%

Vertebral and Femoral Bone Mineral Density (BMD) Assessment with Dual-Energy CT versus DXA Scan in Postmenopausal Females

Stoppino,

Piscone,

Saccone

et al. 2024

J. Imaging

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This study aimed to demonstrate the potential role of dual-energy CT in assessing bone mineral density (BMD) using hydroxyapatite–fat material pairing in postmenopausal women. A retrospective study was conducted on 51 postmenopausal female patients who underwent DXA and DECT examinations for other clinical reasons. DECT images were acquired with spectral imaging using a 256-slice system. These images were processed and visualized using a HAP–fat material pair. Statistical analysis was performed using the Bland–Altman method to assess the agreement between DXA and DECT HAP–fat measurements. Mean BMD, vertebral, and femoral T-scores were obtained. For vertebral analysis, the Bland–Altman plot showed an inverse correlation (R2: −0.042; RMSE: 0.690) between T-scores and DECT HAP–fat values for measurements from L1 to L4, while a good linear correlation (R2: 0.341; RMSE: 0.589) was found for measurements at the femoral neck. In conclusion, we demonstrate the enhanced importance of BMD calculation through DECT, finding a statistically significant correlation only at the femoral neck where BMD results do not seem to be influenced by the overlap of the measurements on cortical and trabecular bone. This outcome could be beneficial in the future by reducing radiation exposure for patients already undergoing follow-up for chronic conditions.

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“…In the evaluation of bone tissue, the application of μCT as well as histomorphometric analysis might be of great assistance ( Gielkens et al ., 2008 ). There are standards for detecting osteoporosis in humans, the dual-energy x-ray absorptiometry (DXA) scan being the gold standard ( Touban et al ., 2022 ). However, it is vital to keep in mind that bone BV/TV can vary from case to case, depending on a variety of factors, including hormones, but also lifestyle behavior, level of physical activity, and medication usage.…”

Section: Discussionmentioning

confidence: 99%

Histomorphometry and μCT scan analysis of osteoporosis in spayed female dogs

Kostenko¹,

ius²,

Maknickas³

2023

Open Vet J

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Background: Both humans and small animals suffer from similar metabolic and structural diseases that impact the musculoskeletal system; however, instead of studying animal disease in its own right, animals are more often used as models for research into various human ailments, such as osteoporosis. There are few studies indicating that animals may suffer from osteoporosis, which raises the question of why small animals, which we believe to be equally susceptible, receive so little attention. With this research, we hope to draw the attention of researchers to the fact that the examination of animals for this disease is just as important as the examination of humans; human osteoporosis research receives a great deal of attention, while animals and their health are neglected. Aims: We aimed to analyse the bone volume fraction (BV/TV) and thickness of first (L1) and second (L2) lumbar vertebrae samples from five cadavers using histomorphometric analysis. In addition, we aimed to investigate one cadaver using microcomputed tomography (micro-CT) imaging. Methods: The L1 and L2 vertebrae from five dog carcasses were used to evaluate the BV/TV and the trabecular thicknesses. We used precise sampling criteria, and also developed a methodological approach to the study of the vertebrae. Using semi-automated methods, we performed histomorphometric analysis and microcomputed tomography data analysis. Results: We used five dog cadavers in this research. During the histomorphometry study, we observed that the lowest L1 BV/TV ratio was 7.88% and the highest was 23.08%. The L2 vertebrae BV/TV ranged from 11.58 to 23.7%. The L1 and L2 lumbar trabeculae thicknesses were also measured. L1's smallest trabecula was 17.34 microns and its largest was 31.88. The L2 vertebrae trabecula thickness was 18.76 to 30.75 microns. BV/TV and trabecular thickness were positively correlated (and vice versa). The two-tailed P value was less than 0.00001. This difference is statistically significant. After microcomputed tomography analysis, we discovered regions in the vertebral body with low porosity; these cavities are usually filled with connective tissue. The bone tissue in these areas is more vulnerable, meaning fracture risk has increased. Conclusions: Animals should not just be considered as models for osteoporosis in humans, but also as potential patients. A single test, such as histomorphometry, may not be sufficient; more advanced technology, such as microcomputed tomography, is required, since it reveals the pores that make the vertebral column more brittle and susceptible to fracture.

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Computed Tomography Measured Psoas Cross Sectional Area Is Associated With Bone Mineral Density Measured by Dual Energy X-Ray Absorptiometry

Cited by 10 publications

References 29 publications

Regular sling core stabilization training improves bone density based on calcium and vitamin D supplementation

Regular sling core stabilization training improves bone density based on calcium and vitamin D supplementation

Vertebral and Femoral Bone Mineral Density (BMD) Assessment with Dual-Energy CT versus DXA Scan in Postmenopausal Females

Histomorphometry and μCT scan analysis of osteoporosis in spayed female dogs

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