Computer-Assisted CT-Guided Stereotactic Biopsy and Brachytherapy of Brain Tumors

Abstract

From March 1991 to September 1993, 26 patients (aged 4–78 years) with brain tumors (4 glioblastoma multiforme, 10 nonglioblastoma multiforme, 1 mixed oligoastrocytoma, 2 carniopharyngiomas, 2 meningiomas and 7 metastases) were treated with stereotactic techniques at the Centro Internacional de Restauracion Neurológica, La Habana, Cuba. A total of 28 stereotactic surgical procedures were performed with no operative mortality; they included biopsies in all cases, 1 stereotactic microsurgical resection and 12 permanent implants of ¹⁹²Ir, followed by external beam fractionated radiation therapy (40–60 Gy). The present paper shows that the combined use of a stereotactic approach, a comprehensive and reliable stereotactic dosimetric planning system, stereotactic brachytherapy with ¹⁹²Ir and complementary percutaneous radiation treatment constitutes a promising strategy for brain tumor management.

Venture in 101 cranial punctures: A comparative study between frame-based versus frameless biopsy of 101 intracranial space occupying lesion

“…The principle of stereotactic biopsy of ICSOL had evolved over years ever since Horsly and Clarke [4] performed the first stereotactic brain biopsy on the cerebellum of a rat and Spiegel and Wycis, later in 1947, displayed their first human SB using three-dimensional coordinate system using intracranial landmark defined by pneumoencephalography. [5] Maroon et al first reported CT-guided stereotactic system in 1977. [6] In most such cases, conclusive diagnosis can be established by SBs alone.…”

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“…Os protocolos de radioterapia intersticial geralmente consideram a histologia, a definição do limite do volume-alvo (relação com o limite que capta contraste e o edema, biópsia seriada em vários trajetos), o volume das lesões, a localização dos alvos em relação aos núcleos da base, os tratos e os núcleos de nervos cranianos e outras estruturas funcionalmente fundamentais do encéfalo e a associação com cirurgias, telerradioterapia ou outros procedimentos adjuvantes 127,149,159,174,237 . Em virtude da conformação irregular das lesões, especialmente após as intervenções operatórias, o planejamento da radioterapia intersticial deve ser rigoroso e detalhado.…”

Computed Tomography Guided Stereotactic Biopsy of Cerebral Lesion: A Safe Diagnostic Procedure

“…This in turn can be translated from space localization to the target set point in a patient. The principle has evolved over years ever since Horsely and Clarke 14 performed the fi rst stereotactic brain biopsy on the cerebellum of a rat and Spiegel-Wycis, later in 1947, displayed their fi rst human stereotactic technique using three dimensional coordinate system using intracranial land mark defi ned by pneumoencephalography 22 . Maroon et al fi rst reported CT guided stereotactic system in 1977.…”