Conceptualization and characterization of “primary” and “secondary” cognitive impairment in schizophrenia

Vita, Antonio; Nibbio, Gabriele; Barlati, Stefano

doi:10.1016/j.psychres.2024.116126

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2024

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Cited by 3 publications

References 293 publications

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The economic burden of schizophrenia spectrum disorders: clinical and functional correlates and predictors of direct costs. A retrospective longitudinal study

Calzavara Pinton,

Nibbio,

Bertoni

et al. 2024

Psychiatry Research

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The economic burden of schizophrenia spectrum disorders: clinical and functional correlates and predictors of direct costs. A retrospective longitudinal study

Calzavara Pinton,

Nibbio,

Bertoni

et al. 2024

Psychiatry Research

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Analysis of Differentially Expressed Genes in Schizophrenia Based on Bioinformatics and Corresponding Mrna Expression Levels

Tian,

Liu,

Liu

et al. 2024

Preprint

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Is It Possible to Combine Non-Invasive Brain Stimulation and Evidence-Based Psychosocial Interventions in Schizophrenia? A Critical Review

Lisoni,

Nibbio,

Baglioni

et al. 2024

Brain Sciences

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In schizophrenia, it was suggested that an integrated and multimodal approach, combining pharmacological and non-pharmacological interventions, could improve functional outcomes and clinical features in patients living with schizophrenia (PLWS). Among these alternatives, evidence-based psychosocial interventions (EBPIs) and Non-Invasive Brain Stimulation (NIBS) represent feasible treatment options targeting the clinical features that are unmet needs of PLWS (especially negative and cognitive symptoms). As no clear evidence is available on the combination of these non-pharmacological approaches, this review aimed to collect the available literature on the combination of EBPIs and NIBS in the treatment of PLWS. We demonstrated that the field of combining EBPIs and NIBS in schizophrenia is in its infancy, as only 11 studies were reviewed. In fact, only a few trials, with divergent results, combined these non-pharmacological modalities; while emerging evidence is available on the combination of cognitive remediation and rTMS/iTBS, inconclusive results were obtained. Conversely, albeit preliminary, more solid findings are available on the combination of HF-rTMS and family intervention. Moreover, despite the fact that cognitive activation could not be considered an EBPI, promising results are available in combination with tDCS to improve the working memory domain. To overcome these limitations, we considered several methodological issues to promote research in this field.

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Conceptualization and characterization of “primary” and “secondary” cognitive impairment in schizophrenia

Cited by 3 publications

References 293 publications

The economic burden of schizophrenia spectrum disorders: clinical and functional correlates and predictors of direct costs. A retrospective longitudinal study

The economic burden of schizophrenia spectrum disorders: clinical and functional correlates and predictors of direct costs. A retrospective longitudinal study

Analysis of Differentially Expressed Genes in Schizophrenia Based on Bioinformatics and Corresponding Mrna Expression Levels

Is It Possible to Combine Non-Invasive Brain Stimulation and Evidence-Based Psychosocial Interventions in Schizophrenia? A Critical Review

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