Condensing Effect of Cholesterol: A Physical Model

The Effect of Cholesterol on the Binding and Insertion of Cytochrome b5 into Liposomes of Phosphatidylcholines

“…In mixed monolayers containing cholesterol, the total surface area is not a simple additive function of individual molecular areas, but demonstrates negative deviation from linearity (Zatz, 1974). This has been termed the Condensing Effect.…”