“…The reproducibility of the constructed MSP was found to be questionable in 13 of the included studies [16, 17, 21-26, 32, 9, 41, 46, 52] as they failed to report the reliability assessment, which led to a rating of 'high' risk of concern; however, the overall risk was judged to be 'low' in the index test domain. Regarding the reference standard domain, nine studies with ambiguous reference standards were considered to have 'unclear' risk [17,26,31,38,39,41,49,50,52], while the majority of the studies were deemed to have 'low' risk. The Supplementary Figure includes a detailed presentation of the study quality and risk of bias assessment.…”