“…Regarding the treatment for CCC, topical Nystatin is the most common treatment, followed by topical Clotrimazole 1 . On the other hand, systemic antifungal therapy has efficacy in neonatal sepsis, weight <1500 g, previous treatment with broad-spectrum antibiotics, respiratory distress, positive cultures, and immunodeficiency [5][6][7][8][9] . Management includes non-azole antifungal Amphotericin B, 1mg/kg for Amphotericin B deoxycholate, and 5 mg/kg for lipid-associated Amphotericin B preparations.…”