Congenital Complete Heart Block: Single Tertiary Centre Experience

Yan, Jennifer; Varma, Suraj; Malhotra, Atul; Menahem, Samuel

doi:10.1016/j.hlc.2012.05.784

Cited by 7 publications

(10 citation statements)

References 22 publications

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“…34 publications described terms and limits, which are selected 20. Of these, seven publications correspond to case reports with literature review, conducted in the United States 4,5 were obtained; Colombia; 10 Germany; 14 Canada and the United States; 15 Australia 16 and Italy. 17 The other 14 selected publications covering 9 literature reviews 2,3,18-22 and five cohort studies being 3 retrospective 8,11,13 and two forward.…”

Section: Resultsmentioning

confidence: 99%

“…On postnatal handling, Yang et al reported a series of cases in 2012 in which they analyzed a cohort of 15 patients with complete AV block, finding that 87% of infants requiring implantation of a pacemaker as definitive management. 16 The timing of pacemaker implantation depends on whether the patient is symptomatic, since the ventricular rate of complete AV block is usually not sufficient to maintain cardiac output neonate. 22 A lower heart rate 55 bpm to an absolute indication for use of such attachments.…”

Section: Treatmentmentioning

confidence: 99%

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Fetal complete atrioventricular block: diagnostic and therapeutic approach: a case report and review of the literature

Poveda-Rojas

Vélez-Tirado

Bonilla-Cortes

et al. 2018

OGIJ

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Objective: To report a case of congenital complete atrioventricular block and perform a literature review of diagnosis and treatment. Materials and methods: The case of a pregnant 27 year old who consults a general hospital of high complexity, with a pregnancy of 33 weeks single fetus diagnosed with complete atrioventricular block and dilated cardiomyopathy secondary is reported. Prenatal management began with Betamimetic with poor response so it was necessary to end the pregnancy. The newborn requires implantation of ventricular pacemakers in the first day of life with excellent results in follow-up to 1 year. Medline, Lilacs, SciELO, by the words: literature review published in the data bases is done "fetal complete atrioventricular block", "congenital complete heart block" with limits year from 2000 to 2016, Spanish and English. Results: 21 publications were obtained; seven case reports ten literature reviews four cohort studies. The diagnosis is based on fetal echocardiography showing valvular regurgitation, myocardial/valvular hyperechogenicity-endocardial fibroelastosis, premature atrial contractions and pericardial effusion. Prenatal treatment with respect to the corticosteoides and Betamimetics, are the most commonly used medications. Treatment of severe refractory neonatal bradiarritimia may require implantation of a pacemaker as definitive management Conclusion: Congenital third-degree AV block requires early diagnosis and treatment is associated with high perinatal morbidity and mortality. More studies are needed methodological quality that allow other options to endorse promising therapeutic regimens.

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Section: Resultsmentioning

confidence: 99%

Section: Treatmentmentioning

confidence: 99%

Fetal complete atrioventricular block: diagnostic and therapeutic approach: a case report and review of the literature

Poveda-Rojas

Vélez-Tirado

Bonilla-Cortes

et al. 2018

OGIJ

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“…Sobre el manejo posnatal, Yang et al reportan una serie de casos en el año 2012 en la cual analizaron una cohorte de 15 pacientes con bloqueo AV completo, y encontraron que el 87 % de los recién nacidos requirió implantación de marcapasos como manejo definitivo (16). El momento de la implantación del marcapasos depende de si el paciente está sintomático, dado que la frecuencia ventricular de un bloqueo AV completo suele no ser suficiente para mantener el gasto cardiaco del neonato (22).…”

Section: Resultsunclassified

“…En los últimos años se han desarrollado marcapasos cada vez más pequeños y con baterías de mayor duración, lo cual prolonga el tiempo antes de una primera reintervención en este grupo de pacientes (16). En un reporte de casos con revisión de literatura se documenta que la tendencia es a implantar menos marcapasos unicamerales, prefiriendo los bicamerales (mayor dificultad técnica en el momento de la inserción), ya que ofrecen la ventaja de mayor respuesta sinusal y los beneficios hemodinámicos de la sincronía auriculoven tricular (17).…”

Section: Resultsunclassified

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Bloqueo auriculoventricular fetal completo: enfoque diagnóstico y terapéutico; reporte de caso en Bogotá, Colombia y revisión de la literatura

Poveda-Rojas¹,

Vélez-Tirado²,

Bonilla-Cortes³

et al. 2017

Rev. Colomb. Obstet. Ginecol.

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RepoRte de caso Rev Colomb Obstet Ginecol 2017;68:305-312 RESUMENObjetivo: reportar un caso de bloqueo auriculoventricular completo congénito y realizar una revisión de la literatura del diagnóstico y tratamiento. Materiales y métodos: se reporta el caso de una gestante de 27 años quien consulta a un hospital general de alto nivel de complejidad, con un embarazo de 33 semanas, con feto único, con diagnóstico de bloqueo auriculoventricular completo y cardiomiopatía dilatada secundaria. Se inició manejo prenatal con betamimético con pobre respuesta, por lo cual fue necesario finalizar el embarazo. El recién nacido requiere implantación de marcapasos ventricular en el primer día de vida con excelentes resultados en el seguimiento a un año. Se realiza revisión de la literatura publicada en las bases de datos: Medline vía PubMed, Lilacs y SciELO mediante los términos: "fetal complete atrioventricular block", "congenital 1 Ginecoobstetra, Universidad Militar Nueva Granada, Bogotá (Colombia).dianeporo718@hotmail.com 2 Pediatra, Universidad Militar Nueva Granada, Bogotá (Colombia). complete heart block", con límites de año de 2000 a 2016, en español e inglés. Resultados: se obtuvieron 21 publicaciones; siete reportes de caso, diez revisiones de literatura, cuatro estudios de cohorte. El diagnóstico se basa en la ecocardiografía fetal para determinar el intervalo PR, la relación auriculoven tricular y la detección de anomalías intracardiacas, entre las que se encuentran: regurgitación valvular, hiperecogenicidad miocárdi-ca/valvular-fibroelastosis endocárdica, contracciones atriales prematuras y efusión pericárdica. Respecto al tratamiento prenatal, los medicamentos más utilizados son los corticoesteroides y los betamiméticos. El tratamiento de la bradiarritimia severa refractaria neonatal puede requerir la implantación de un marcapaso como manejo definitivo. Conclusión: el bloqueo AV congénito de tercer grado requiere diagnóstico temprano y tratamiento oportuno, ya que se acompaña de alta morbimortalidad perinatal. Se requieren estudios con mayor calidad metodológica que permitan avalar otras opciones y esquemas terapéuticos prometedores. Palabras clave: bradiarritmia, bloqueo atrioventricular, lupus eritematoso sistémico.

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Maternal autoimmune disease and birth defects in the National Birth Defects Prevention Study

Howley

Browne

Zutphen

et al. 2016

Birth Defects Research

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Background Little is known about the association between maternal autoimmune disease or its treatment and the risk of birth defects. We examined these associations using data from the National Birth Defects Prevention Study, a multi-site, population-based, case–control study. Methods Analyses included 25,116 case and 9897 unaffected control infants with estimated delivery dates between 1997 and 2009. Information on autoimmune disease, medication use, and other pregnancy exposures was collected by means of telephone interview. Adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were estimated for birth defects with five or more exposed cases; crude ORs and exact 95% CIs were estimated for birth defects with three to four exposed cases. Results Autoimmune disease was reported by 373 mothers (279 case and 94 control mothers). The majority of birth defects evaluated were not associated with autoimmune disease; however, a statistically significant association between maternal autoimmune disease and encephalocele was observed (OR, 4.64; 95% CI, 1.95–11.04). Eighty-two mothers with autoimmune disease used an immune modifying/suppressing medication during pregnancy; this was associated with encephalocele (OR, 7.26; 95% CI, 1.37–24.61) and atrial septal defects (OR, 3.01; 95% CI, 1.16–7.80). Conclusion Our findings suggest maternal autoimmune disease and treatment are not associated with the majority of birth defects, but may be associated with some defects, particularly encephalocele. Given the low prevalence of individual autoimmune diseases and the rare use of specific medications, we were unable to examine associations of specific autoimmune diseases and medications with birth defects. Other studies are needed to confirm these findings.

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Congenital Complete Heart Block: Single Tertiary Centre Experience

Cited by 7 publications

References 22 publications

Fetal complete atrioventricular block: diagnostic and therapeutic approach: a case report and review of the literature

Fetal complete atrioventricular block: diagnostic and therapeutic approach: a case report and review of the literature

Bloqueo auriculoventricular fetal completo: enfoque diagnóstico y terapéutico; reporte de caso en Bogotá, Colombia y revisión de la literatura

Maternal autoimmune disease and birth defects in the National Birth Defects Prevention Study

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