Congenital Grouped Albinotic Spots: New Insights on the Pathophysiology Based on Multimodal Retinal Imaging

Abstract

The terms “congenital grouped albinotic spots” (CGAS) and “polar bear tracks” refer to a rare, benign retinal disorder of unknown etiology characterized by multiple, predominantly unilateral, variably sized, well-circumscribed, flat white retinal spots organized in groups. To date, very few cases of CGAS have been reported. The authors describe a case of CGAS thoroughly characterized by multimodal imaging over an 8-year follow-up, aiming to provide new insights on the pathophysiology of this entity. This is the first report where a long follow-up combined with up-to-date imaging technology is used to characterize CGAS. [ Ophthalmic Surg Lasers Imaging Retina . 2020;51:236–238.]

High-Resolution Spectral Domain Optical Coherence Tomography of Congenital Grouped Albinotic Spots

“…Although multimodal imaging features have been reported, the histologic basis of this entity remains unknown. 2 The purpose of this report was to reassess CGAS features using a high-resolution spectral-domain optical coherence tomography (High-Res OCT) prototype (3 µ m of axial resolution) correlated with multimodal imaging analysis.…”