2023
DOI: 10.1002/ppul.26376
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Congenital lobar emphysema: A rare cause of respiratory failure in neonates

Abstract: Congenital lobar overinflation, also known as congenital lobar emphysema (CLE), is an uncommon (1/20,000-30,000 live births) abnormality characterized by hyperinflation of one or more pulmonary lobes, usually with contralateral displacement of the mediastinum.

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“…CLE can be symptomatic in the neonatal period but is most often discovered from one to six months. It manifests itself by recurrent wheezing, cyanosis, wheezing, whining, and in other more severe cases tachypnea and acute respiratory failure [ 11 ]. In the study of Cataneo et al, respiratory symptoms were present in 60% of cases from birth [ 9 ].…”
Section: Discussionmentioning
confidence: 99%
“…CLE can be symptomatic in the neonatal period but is most often discovered from one to six months. It manifests itself by recurrent wheezing, cyanosis, wheezing, whining, and in other more severe cases tachypnea and acute respiratory failure [ 11 ]. In the study of Cataneo et al, respiratory symptoms were present in 60% of cases from birth [ 9 ].…”
Section: Discussionmentioning
confidence: 99%