Congenital, Self-regressing Tufted Angioma

Browning, John; Frieden, Ilona J.; Baselga, Eulàlia; Wagner, Annette; Metry, Denise

doi:10.1001/archderm.142.6.749

Cited by 47 publications

(29 citation statements)

References 12 publications

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“…10 Most TA persists and worsens slightly over time, 11 although some also spontaneously regress. 12,13 KHE is invasive, with a mortality rate as high as 30%. 14 Therefore, increased knowledge of imaging findings associated with KHE and TA may be helpful in determining appropriate diagnoses because TA and KHE without KMP can be easily mistaken for other hemangiomas.…”

Section: Discussionmentioning

confidence: 99%

Ultrasonography and magnetic resonance imaging features of kaposiform hemangioendothelioma and tufted angioma

Gong

Ying

Zhang

et al. 2019

The Journal of Dermatology

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Kaposiform hemangioendothelioma (KHE) and tufted angioma (TA) primarily occurring in infants are difficult to distinguish. This study evaluated ultrasonography (US) and magnetic resonance imaging (MRI) features of KHE and TA. Pathologically proven TA (n = 21) and KHE (n = 40 [11 KHE + Kasabach–Merritt phenomenon [KMP]]) occurring between January 2015 and December 2017 were reviewed. US (n = 61) and MRI (n = 50) findings were retrospectively evaluated. On US, KHE and TA lesions were subcutaneous, while 40% of KHE exhibited an infiltrative pattern extending into adjacent muscles. Of TA lesions, 42.9% were hyperechoic and 96.15% of KHE lesions exhibited mixed echogenicity. Of TA lesions, 76.2% exhibited well‐defined margins and all KHE lesions exhibited ill‐defined margins. The depth and vascular density of KHE and KHE + KMP were significantly increased compared with TA. The arterial peak systolic blood flow velocity of KHE + KMP was significantly higher than that in TA and KHE. KHE and KHE + KMP were significantly harder than TA on elastography. 3‐D color Doppler revealed branch‐shape blood flow for KHE and KHE + KMP lesions; for TA, it revealed a dot‐like and striped pattern. Considering MRI findings, KHE and KHE + KMP were more likely to exhibit diffuse heterogeneous enhancement after contrast than TA. KHE was infiltrative and more likely to be thick, hypoechoic, ill‐defined, richly vascular and hard than TA on US. KHE lesions were subcutaneous and reticular, with heterogeneous enhancement on MRI. Awareness of these features should prompt radiologists in the differential diagnosis of pediatric masses.

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Section: Discussionmentioning

confidence: 99%

Ultrasonography and magnetic resonance imaging features of kaposiform hemangioendothelioma and tufted angioma

Gong

Ying

Zhang

et al. 2019

The Journal of Dermatology

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“…Rare association of Port wine stain with TA is also reported [5,17]. Spontaneous regression is known, but is exceptionally rare and regression may occur over a period varying from months to years [18,19]. …”

Section: Discussionmentioning

confidence: 99%

Tufted angioma (Angioblastoma) of eyelid in adults-report of two cases

Mittal

Tripathy

2013

Diagn Pathol

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Tufted angioma, first recognized in Japanese literature as “Angioblastoma of Nagakawa”, is a rare benign vascular tumour with a variable clinical presentation. It commonly manifests as a macule, papule or nodule in infancy or childhood in the region of the upper trunk and neck. Here in we report two cases of this rare progressive angioma as lesions of the eyelid in adults. Tufted angioma has a classical “cannon ball” like appearance of vascular tufts on histopathology. Immunohistochemical staining with actin highlights the spindly stromal cells surrounding the capillaries. Complete physical examination and haematological work up is recommended in patients with tufted angioma to exclude rare association of port wine stain and Kasabach-Merritt syndrome with this rare entity. To the best of our knowledge, our cases illustrate the first case report of tufted angioma presenting as an eyelid lesion.Virtual SlidesThe virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1230909536950947.

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“…The case analysed showed a vascular lesion with small, angiomatous lobules made of poorly canalised, endothelial-lined, glucose transporter protein 1 (GLUT1)-negative vessels and of solid areas. Cannonballs of capillaries in the dermis with dilated lymphatic vessels are typical features of TA3 4 (figure 3). …”

Section: Answermentioning

confidence: 99%