Congenital tuberculosis after in vitro fertilization presenting with endobronchial granuloma

Venturini, Elisabetta; Montagnani, Carlotta; Boldrini, Antonio; Moroni, Marco; Chiappini, Elena; Martino, Maurizio de; Galli, Luisa

doi:10.1016/j.pedneo.2018.02.001

Cited by 3 publications

(1 citation statement)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…While IVF has become a relatively common treatment method used for infertile women in recent years, many women are not tested for M. tuberculosis before undergoing IVF protocols ( 10 , 13 ). The application of IVF may thereby emerge as a potential risk factor for congenital tuberculosis ( 14 ). Samedi et al ( 15 ) reported a case of congenital tuberculosis following IVF in which the mother exhibited uncontrollable epileptic seizures during preterm birth; these authors isolated M. tuberculosis in the maternal placenta, urine, gastric aspirates, and sputum.…”

Section: Discussionmentioning

confidence: 99%

Congenital tuberculosis in a neonate following in vitro fertilization-embryo transfer: A case report

Zhuang

Yang

et al. 2022

Front. Pediatr.

View full text Add to dashboard Cite

BackgroundCongenital tuberculosis is becoming increasingly common, but congenital tuberculosis infection in neonates following in vitro fertilization and embryo transfer (IVF-ET) has been rarely reported; a diagnosis of congenital tuberculosis is often delayed due to the non-specificity of maternal IVF treatments and clinical manifestations during pregnancy—particularly in low-birth-weight preterm infants.Case presentationWe herein report a case of congenital tuberculosis. The infant was born at 27+5 weeks of gestation and was admitted to the hospital due to hypopnea after birth. Due to a poor response to treatment, we conducted pathogenic microorganism metagenomic analysis to assess the nucleotide sequences within the Mycobacterium tuberculosis complex. After collecting sputum, the strains from the tuberculosis analysis were isolated and confirmed. From a detailed examination of the mother and in accordance with the child's congenital tuberculosis, we confirmed the diagnosis of pelvic tuberculosis.ConclusionIVF treatment and pregnancy can exacerbate latent tuberculosis, especially in women from a family with a history of tuberculosis infections. We posit that the optimal way to prevent neonatal congenital tuberculosis in IVF-ET is to procure a detailed maternal medical or family history and to identify and treat maternal tuberculosis during IVF treatment.

show abstract

Section: Discussionmentioning

confidence: 99%