Congenital Tuberculosis, Still a Problem

Asensi, F.; Otero, M. C.; Pérez-Tamarit, D; Serrano, E.; Llanes, S.; Santos, M.

doi:10.1097/00006454-199003000-00021

Cited by 12 publications

(2 citation statements)

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“…It is usually found in the babies of mothers whose disease is asymptomatic during pregnancy or at birth,3 , 4 as in our two cases. Congenital tuberculosis should be distinguished from acquired neonatal tuberculosis, in which the infant is infected after birth by an adult suffering from contagious pulmonary tuberculosis.…”

Section: Discussionsupporting

confidence: 49%

Congenital tuberculosis in premature twins after in vitro fertilisation

Altunhan

Keser²,

Pekcan³

et al. 2009

Case Reports

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Genital tuberculosis is a major cause of infertility in countries where tuberculosis is endemic. With recent advances in assisted reproductive technology, women with tuberculous endometritis may become pregnant and ultimately have children with congenital tuberculosis. In vitro fertilisation represents a useful treatment for infertility. Congenital tuberculosis is a rare and severe, rapidly progressive, disease. Making an early diagnosis of congenital tuberculosis is difficult, because it can mimic many neonatal illnesses. To the best of our knowledge, we report the first cases of premature twins with congenital tuberculosis following in vitro fertilisation. After the diagnosis of genital tuberculosis in the mother, the twins were screened and diagnosed for tuberculosis. The twins dramatically improved after anti-tuberculosis therapy. We also wish to draw attention to the importance of searching for genital tuberculosis as the possible cause of congenital infection, even if the mother is asymptomatic.

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