Congestive heart failure due to hypertensive ventricular diastolic dysfunction

Iriarte, Marian; Olea, Jaime Pérez; Sagastagoitia, D; Molinero, E; Murga, Nekane

doi:10.1016/s0002-9149(99)80491-3

Cited by 31 publications

(23 citation statements)

References 15 publications

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“…Systemic hypertension has been associated with many long term complications including systolic and diastolic heart failure, stroke, and myocardial infarction (10)(11)(12). Diastolic dysfunction associated with hypertension, especially of the left ventricle, has been linked with increasing mortality and morbidity (13,14).…”

Section: Discussionmentioning

confidence: 99%

Carotid atherosclerosis and right ventricular diastolic dysfunction in a sample of hypertensive Nigerian patients

Akintunde¹,

Adebayo

Aremu

et al. 2013

Croat Med J

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AimTo determine the association of carotid atherosclerosis and right ventricular diastolic dysfunction (DD) among treated hypertensive Nigerian patients. MethodsThis was a single center cross-sectional study performed at the Cardiology Clinic of LAUTECH Teaching Hospital, Ogbomoso, Nigeria between January and December 2012. The study included 122 hypertensive Nigerians (mean age, 57.3 ± 14.7 years, 36.9% women). Patients' clinical, demographic, and echocardiographic parameters were obtained. Diastolic dysfunction was assessed with the trans-tricuspid Doppler flow.Results Patients with DD were significantly older than those with normal diastolic function. Mean and maximum carotid intima media thickness measurements were significantly higher among patients with right ventricular DD than in those with normal diastolic function. Mean systolic blood pressure (148.3 ± 31.9 vs 128.0 ± 2.8 mm Hg, P = 0.049) and interventricular septal thickness in diastole (12.8 ± 2.3 vs 11.6 ± 2.8 mm, P = 0.048) were significantly higher and tricuspid annular pulmonary systolic excursion (33.6 ± 4.9 vs 23.0 ± 4.2 mm, P = 0.035) was significantly lower in patients with right ventricular DD than in those with normal diastolic function. Carotid intima media thickness measurements were correlated with early trans-tricuspid Doppler flow and early transtricuspid diastolic flow/late right atrial transtricupsid diastolic flow ratio.Conclusion Right ventricular DD in hypertensive patients was significantly correlated with increased carotid atherosclerosis. Carotid intima media thickness measurements may therefore be a surrogate marker for DD in hypertensive subjects.

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Section: Discussionmentioning

confidence: 99%

Carotid atherosclerosis and right ventricular diastolic dysfunction in a sample of hypertensive Nigerian patients

Akintunde¹,

Adebayo

Aremu

et al. 2013

Croat Med J

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“…Left ventricular diastolic dysfunction is the first discernible manifestation of heart disease in hypertensive patients 11,12 . Pulsed Doppler transmitral echocardiography can detect left ventricular (diastolic) filling abnormalities in patients with hypertension even before any clinical or electrocardiographic abnormalities are present Keywords: Prevalence, diastolic dysfunction, hypertensive Nigerians.…”

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confidence: 99%

The prevalence of diastolic dysfunction in adult hypertensive Nigerians

Ike¹,

Ikeh²

2006

Ghana Medical Journal

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“…LVH produces an increase in wall thickness at the expense of chamber volume, due to hypertrophy of the myocytes and by a parallel alignment of the sarcomeres [12]. It has been proposed that LVH is associated with a specific hypertensive cardiomyopathy [13,14]. This cardiomyopathy is divided into four different stages, where stage one is hypertension with diastolic relaxation abnormalities and grade four is a dilated cardiomyopathy with reduced ejection fraction.…”

Section: Mechanisms Linking Hypertension To Heart Failurementioning

confidence: 99%

“…Usually, left ventricular diastolic dysfunction precedes systolic dysfunction and therefore diastolic dysfunction is the more common mechanism of HF in hypertensive patients [14]. Table 1 Epidemiological data on the prevalence of hypertension (HT), diabetes (DM), chronic obstructive pulmonary disease (COPD) and anemia in patients with heart failure (HF)…”

Section: Mechanisms Linking Hypertension To Heart Failurementioning

confidence: 99%

Frequent non-cardiac comorbidities in patients with chronic heart failure

Dahlström

2005

European Journal of Heart Failure

104

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Heart failure (HF) in elderly patients is associated with more diffuse symptoms and signs due to the presence of other noncardiac comorbidities. This can cause difficulties in assessing the correct diagnosis and initiating appropriate therapy. The four most frequently occurring noncardiac comorbidities and therapies used to treat them are discussed in the present paper.Hypertension is an important precursor of HF, and is still the most common risk factor for HF in the general population. About 50% of patients with untreated hypertension will develop HF. Pressure overload leads to the development of left ventricular hypertrophy (LVH) and diastolic dysfunction.Diabetes, which occurs in about 20-30% of patients with HF, is an important comorbidity resulting in morphological and metabolic disturbances affecting myocardial blood flow and hormonal regulation leading to a poor outcome and necessitating aggressive conventional treatment.Chronic obstructive pulmonary disease (COPD), occurs in approximately 20-30% of heart failure patients, and may complicate HF treatment, it is therefore important to recognize and treat it effectively.Finally, the early detection of anemia, which occurs in 20-30% of HF patients, is important since it is associated with functional impairment and increased mortality and morbidity. Combined treatment with erythropoietin and intravenous iron has shown beneficial effects on clinical symptoms and morbidity.In conclusion early detection of concomitant diseases in patients with HF is important and should be considered carefully when initiating therapy.

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Congestive heart failure due to hypertensive ventricular diastolic dysfunction

Cited by 31 publications

References 15 publications

Carotid atherosclerosis and right ventricular diastolic dysfunction in a sample of hypertensive Nigerian patients

Carotid atherosclerosis and right ventricular diastolic dysfunction in a sample of hypertensive Nigerian patients

The prevalence of diastolic dysfunction in adult hypertensive Nigerians

Frequent non-cardiac comorbidities in patients with chronic heart failure

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