Consensus-Based Evaluation of Outcome Measures in Pediatric Stroke Care: A Toolkit

Feldman, Susan C.; Beslow, Lauren A.; Felling, Ryan J.; Malone, Laura A.; Waak, Michaela; Fraser, Stuart; Bakeer, Nihal; Lee, Jo Ellen M.; Шерман, В. Д.; Howard, Melissa; Cavanaugh, Beth Anne; Westmacott, Robyn; Jordan, Lori C.

doi:10.1016/j.pediatrneurol.2023.01.009

Cited by 7 publications

(4 citation statements)

References 188 publications

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“…Para evaluar la recuperación neurológica tras un ictus pediátrico se han elaborado numerosas escalas, pero las únicas validadas para este rango de edad son la escala PSOM (Pediatric Stroke Outcome Measure), el cuestionario psRRQ (Pediatric Stroke Recurrence and Recovery Questionnaire) y la escala PSQLM (Pediatric Stroke Quality of Life Measure) 35 .…”

Section: Ictus Posnatalunclassified

Ictus pediátrico

Menéndez-Valladares,

Alonso-Pérez,

Fuerte-Hortigón

et al. 2024

KRANION

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El ictus en la edad pediátrica es una emergencia neurológica infradiagnosticada. Solo se diagnostican en fase aguda el 48% de estos ictus. Con frecuencia el diagnóstico es tardío. Como consecuencia, los supervivientes van a presentar importantes secuelas motoras, cognitivas o del lenguaje. Ante la presencia de signos de alarma de menos de 24 horas de evolución, debe activarse el «código ictus pediátrico». Este protocolo ya ha sido implantado en algunos centros de la red hospitalaria nacional. La clínica de sospecha en el niño es muy inespecífica. Lo ideal sería disponer de un panel de biomarcadores validado para ayudar al diagnóstico. La encefalopatía hipóxico-isquémica neonatal es la patología neurovascular pediátrica en la que más se han centrado los estudios de biomarcadores. La clasificación del ictus es dependiente de la naturaleza de la lesión cerebral (isquémica o hemorrágica) y de la edad del niño: perinatal (entre la semana 20 de gestación y los 28 días de vida) y posnatal (entre el día 28 y los 15-19 años). Los biomarcadores que presentan mayor potencial se relacionan con el tejido nervioso: proteína S100 de unión al calcio (S100B), enolasa neuronal específica (NSE), proteína ácida fibrilar glial (GFAP), ubiquitina carboxiterminal hidrolasa L1 (UCHL-1) y activina A; con el sistema neurovascular: adrenomedulina (AM); con la inflamación: interleucina-6 (IL-6); y con el estrés oxidativo: F2-isoprostanos. Por otro lado, las pruebas complementarias a posteriori, como los paneles genéticos, van a permitir conocer la etiología del ictus.

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Section: Ictus Posnatalunclassified

Ictus pediátrico

Menéndez-Valladares,

Alonso-Pérez,

Fuerte-Hortigón

et al. 2024

KRANION

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“…Similarly, Diamond (2013) reported developmental progression on measures of EF. Executive functions develop through childhood into early adulthood and are important for adaptive goal-oriented behavior (Feldman et al, 2023). Executive dysfunction has been implicated in several pathologies, including but not limited to depression, anxiety, and suicide in late life (Goodkind et al, 2016; Smagula et al, 2017).…”

Section: Literature Reviewmentioning

confidence: 99%

“…EF has consistently formed a significant basis for the majority of batteries aimed at neuropsychological assessments over the past 2 decades (Feldman et al, 2023; Nyongesa et al, 2019). The lack of conceptual and operational definitions provided for executive function/dysfunction raised concerns around measurement and assessment.…”

Section: Literature Reviewmentioning

confidence: 99%

An examination of the Amsterdam Executive Function Inventory (AEFI) in South Africa: A factor analytic study.

Coppin,

Wagener,

Smith

2023

Psychology & Neuroscience

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Research on executive functioning is hamstrung by the lack of access to instrumentation in developing contexts. The exploration of self-report measures of executive functioning is important to address instrumentation challenges. This study aimed to validate the Amsterdam Executive Function Inventory (AEFI) in a sample of adult university students in South Africa. Method: This archival study used secondary research gathered by Coppin (2021). A total of 1,315 students at a South African university completed the AEFI online. Assumption testing was done to confirm that the data supported confirmatory factor analysis (CFA). Cronbach's α was computed to determine internal consistency with this sample. CFA was used to evaluate the factor structure against the theoretical model underpinning the AEFI. Results: The data supported using CFA. Cronbach's α for the overall scale was .74, indicating good stability. For individual subscales, αs ranged between .55 and .67 suggesting adequate reliability. The CFA model showed good fit on five indices after respecification, χ 2 (56) = 266.86, p < .01; chi-square/degrees of freedom ratio = 4.77; root-mean-square error of approximation = .054; comparative fit index = .93; standardized root-mean-square residual = .055; goodness-of-fit index, GFI = .97]. Conclusions: Results of this study suggest that the AEFI is a valid and reliable instrument for use among adult student populations in the South African context. Public Significance StatementThis study provided evidence for the Amsterdam Executive Function Inventory (AEFI) as a valid and reliable instrument. The AEFI was found to be fit for use for the measurement of self-reported executive functioning among adult student populations in South Africa.

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“…As clinical studies revealed the difference between pediatric stroke from adult stroke regarding etiology and prognosis, consensus guidelines for the acute management of pediatric stroke have regularly been updated with the addition of new knowledge [7,10,11,12,13].…”

Section: Introductionmentioning

confidence: 99%

Does time and experience matter in pediatric arterial ischemic stroke intervention? Long term follow up experience

Ozturk,

Bıyıklı,

Unver

et al. 2024

Preprint

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Introduction: Acute ischemic stroke is an important cause of mortality in childhood with variable long term neurological sequelae. This study presents long term follow up outcome data of our center which is a tertiary clinic with a well-organized pediatric stroke team. Method: Medical records of patients diagnosed at pediatric age (28 days-18 years) with acute ischemic stroke between years 2011-2018 in Marmara University Pediatric Neurology Clinic were retrospectively evaluated. Patients whose initial medical intervention was performed by Marmara University Pediatric Emergency unit and had been followed by our clinic for at least 5 years after initial diagnoses were included in this study. The modified Rankin Scale(mRS) and Pediatric Stroke Outcome Measure Short Neuro Exam (PSE-SEN) were performed to all of the patients in addition to final neurological examination. Results: The mean first ischemic stroke age of 32 patients (20 male,62,5%) included in the study was 77,39±61,93 months. First stroke age was grouped as early (≤60 months; n=16) and late (>61 months, n=16). The median time passed from initial symptom to emergency room admission was 15,5 (1-720) hours. The mean follow-up interval of the study group was 85,44±20,52 months and the mean age of the group at the time of the study (present age) was 162,62±64,4 months. Affected vascular territory did not have any significant effect on long-term clinical outcomes (p=0,550). Late stroke age group (>61 months) had a significantly higher rate of normal functional long-term outcome(p=0.023). The younger age group (≤60 months) had longer hospital admission time (24 h vs 9 h). PSOM scores were helpful to detect some mild cognitive and language dysfunctions that did not interfere with daily life. Conclusion: Pediatric Stroke Outcome Measure Short Neuro Exam (PSE-SEN) is helpful to catch mild neurocognitive sequela that can be missed with neurological examination. Considering the fact that time after first symptom is critical for early intervention in acute ischemic stroke patients, stroke teams should be settled in all centrally located medical centers with easy transportation opportunities.

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Consensus-Based Evaluation of Outcome Measures in Pediatric Stroke Care: A Toolkit

Cited by 7 publications

References 188 publications

Ictus pediátrico

Ictus pediátrico

An examination of the Amsterdam Executive Function Inventory (AEFI) in South Africa: A factor analytic study.

Does time and experience matter in pediatric arterial ischemic stroke intervention? Long term follow up experience

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