Consensus conference: Acitretin in combination with UVB or PUVA in the treatment of psoriasis

Lebwohl, Mark; Drake, Lynn A.; Menter, Alan; Koo, John; Gottlieb, Alice B.; Zanolli, Michael D.; Young, Melodie; McClelland, Patricia

doi:10.1067/mjd.2001.116347

Cited by 123 publications

(79 citation statements)

References 67 publications

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“…Although the efficacy ratings of acitretin were not impressive in this study, it was considered to be a convenient, safe and easy to monitor drug in the treatment of psoriasis. Indeed, in monotherapy acitretin is moderately effective, but higher clearance rates are to be expected in combination with phototherapy, of which the considerations were assessed, and long-term studies demonstrate that it is a relatively safe drug [30]. It should be noted that this study focused on chronic plaque psoriasis excluding pustular or erythrodermic psoriasis in which acitretin may be more effective.…”

Section: Discussionmentioning

confidence: 99%

Dermatologists’ Views and Opinions about Photo(chemo)therapy and Conventional Systemic Psoriasis Therapies: Results from a Belgian Survey

Nijsten

Lambert

2006

Dermatology

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Background: Experts’ opinions about old and new psoriasis therapies are well documented. Objectives: To document the views and opinions of a large, diverse group of dermatologists about psoriasis treatment. Participants/Methods: A survey was conducted among Belgian dermatologists. In addition to demographic and professional characteristics, the questionnaire assessed the self-rated level of experience, frequency of use, preference and considerations regarding UVB, PUVA, methotrexate (MTX), cyclosporin (CsA) and acitretin. Multivariate logistic regression analyses were performed to investigate predictors of these dermatologist-based outcomes. Results: Of the 628 contacted dermatologists, 310 responded (response rate of 49.3%). The dermatologists were significantly more experienced with photo(chemo)therapy than with systemic agents (p ≤ 0.02); about half reported none or little experience with MTX and CsA. Also, photo(chemo)therapies were significantly more frequently used than systemic drugs (p ≤ 0.01). In the last year, almost 40% had not used and less than 10% had used MTX or CsA more than 10 times. Despite the limitations of PUVA, it was preferred to UVB, followed by acitretin (± phototherapy), and MTX and CsA were considered final options by most dermatologists. After adjusting for confounding variables, age, years in practice, seeing and treating more patients, residency programme and/or access to UV therapy were significantly associated with limited experience, regular use and/or preference of studied therapies. Conclusion: Either a substantial proportion of the dermatologists does not need or wish to use conventional systemic psoriasis therapies or they may need better and more uniform training during and after their residency. This may improve patient care and patient selection for other treatments.

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Section: Discussionmentioning

confidence: 99%

Dermatologists’ Views and Opinions about Photo(chemo)therapy and Conventional Systemic Psoriasis Therapies: Results from a Belgian Survey

Nijsten

Lambert

2006

Dermatology

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“…Asitretinin dar bant UVB veya PUVA ile kombinasyonu (reUVB, rePUVA), tek başına fototerapiye oranla, yanıtı artıran, iyileşme için gerekli seans sayısını ve kümülatif UV dozunu azaltan bir yaklaşımdır. Bu nedenle, tek başına fototerapi ile yeterince düzelmeyen, hızlı ve daha kısa sürede yanıt gereksinimi olan, şiddetli psoriasis hastalarında tercih edilebilecek etkili bir tedavi yöntemidir (93,94). Retinoid ile UV kombinasyonu farklı şekillerde yapılabilir.…”

Section: Psoriasiste Fototerapiunclassified

Current Approach to Phototherapy Applications in Dermatology Practice: Part 2. Phototherapy in Vitiligo, Mycosis Fungoides, Atopic Dermatitis, Sclerosing Diseases and Psoriasis

Gençosmanoğlu¹

2017

tdd

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“…6 In the treatment of patients with psoriasis, combinations of treatments are commonly used in order to increase efficacy or reduce adverse effects. [7][8][9][10][11] Far less controlled trial data are available on use of combinations of treatments for psoriasis as compared to monotherapy studies.…”

Section: Sommairementioning

confidence: 99%

The Frequent Use of Oral Retinoids in Combination with Other Treatments for Psoriasis: A Retrospective Analysis

Balkrishnan

Camacho

et al. 2004

J Cutan Med Surg

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Consensus conference: Acitretin in combination with UVB or PUVA in the treatment of psoriasis

Cited by 123 publications

References 67 publications

Dermatologists’ Views and Opinions about Photo(chemo)therapy and Conventional Systemic Psoriasis Therapies: Results from a Belgian Survey

Dermatologists’ Views and Opinions about Photo(chemo)therapy and Conventional Systemic Psoriasis Therapies: Results from a Belgian Survey

Current Approach to Phototherapy Applications in Dermatology Practice: Part 2. Phototherapy in Vitiligo, Mycosis Fungoides, Atopic Dermatitis, Sclerosing Diseases and Psoriasis

The Frequent Use of Oral Retinoids in Combination with Other Treatments for Psoriasis: A Retrospective Analysis

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