Contributions by others to the thesis My supervisors Dr Cathy Evans and Dr Kym Runge provided technical support on the project development, the design of the experimental program, data analysis, and critically reviewed the thesis. Dr Barun Gorain provided the data of Barrick's project, which was the start point of this thesis, and valuable guidance on the development of the project with my supervisors Dr Emmy Manlapig and Dr Chris Fountain, who made significant contribution to set up the scope of the project. Dr Elaine Wightman, Kellie White and Dr Cathy Evans provided assistance in the mineralogical characterisation using MLA of Barrick's reference ore. Dr Alex-Anthony Cavallaro performed ToF-SIMS and Dr Chris Bassell performed the XPS analysis of the flotation samples in the University of South Australia. Dr Susana Brito e Abreu provided assistance in the interpretation of the surface analysis data.