Chem. Sci.
 2025
DOI: 10.1039/d4sc06100d
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Constrained TACC3 peptidomimetics for a non-canonical protein–protein interface elucidate allosteric communication in Aurora-A kinase

Diana Gimenez,
Martin Walko,
Jennifer A. Miles
et al.

Abstract: Rational design is used to optimize peptidomimetic inhibitors of the TACC3/Aurora-A kinase interaction.

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