Construction and characterization of a temperature-responsive nanocarrier for imidacloprid based on mesoporous silica nanoparticles

Fe3O4 Magnetic Cores Coated with Metal–Organic Framework Shells as Collectable Composite Nanoparticle Vehicles for Sustained Release of the Pesticide Imidacloprid

“…As described in Figure A, the optimized mass ratio between IMI and Fe 3 O 4 @PDA@UiO-66 was 30:1, at which the DL and EE were 15.87 and 26.45%, respectively. IMI@Fe 3 O 4 @PDA@UiO-66 exhibited a relatively high DL due to the unique pore structures and large surface areas, , which was comparable to bifunctional hairy silica nanoparticles (BHSNs) (16%) with a single large through-hole, but lower than our reported IMI@MSNs (27.47%) of which the surface area (933.23 m 2 ·g –1 ) is larger than that of Fe 3 O 4 @PDA@UiO-66 (502.51 m 2 ·g –1 ). , …”

“…IMI@Fe 3 O 4 @PDA@ UiO-66 exhibited a relatively high DL due to the unique pore structures and large surface areas, 45,46 which was comparable to bifunctional hairy silica nanoparticles (BHSNs) (16%) with a single large through-hole, but lower than our reported IMI@ MSNs (27.47%) of which the surface area (933.23 m 2 •g −1 ) is larger than that of Fe 3 O 4 @PDA@UiO-66 (502.51 m 2 •g −1 ). 4,44 The successful loading of IMI into Fe 3 O 4 @PDA@UiO-66 was verified by performing nitrogen adsorption−desorption measurements (Figure 2B). The N 2 adsorption−desorption isotherm of Fe 3 O 4 @PDA@UiO-66 exhibited a typical IV curve, 47 with an estimated BET specific surface area of 502.51 m 2 •g −1 , which is lower than that of UiO-66 in our previous publication (926.54 m 2 •g −1 ), 29 ascribed to the existence of the Fe 3 O 4 core.…”

“…The pore size of the Fe 3 O 4 @PDA@UiO-66 nanocomposite (Figure S2) was found to be large enough to accommodate IMI molecules (0.65 nm × 0.59 nm × 0.60 nm, simulated by Material Studio software, Figure S3). 44 The DL and EE of IMI into Fe 3 O 4 @ PDA@UiO-66 were optimized by varying the mass ratio between IMI and Fe 3 O 4 @PDA@UiO-66 in DMF solution. As described in Figure 2A, the optimized mass ratio between IMI and Fe 3 O 4 @PDA@UiO-66 was 30:1, at which the DL and EE were 15.87 and 26.45%, respectively.…”

How Advancing are Mesoporous Silica Nanoparticles? A Comprehensive Review of the Literature

“…Due to higher metabolism and inflammation 26 , 27 , 102 in tumor tissues, temperature-responsive systems were introduced. Poly (N-isopropyl acrylamide) (PNIPAAm), 26 , 27 paraffin wax, 103 and glycerophosphate 104 are the most commonly used temperature-sensitive materials for temperature-responsive nanocarriers synthesis. The phase-transition temperatures of these materials are higher than the body temperature.…”

Chitosan‐basedorganic/inorganic composite engineered forUV light‐controlledsmartpH‐responsivepesticide throughin situphoto‐inducedgeneration of acid

“…Specifically, it was reported that nearly four million tons of pesticides are consumed annually for the management of diseases and crop protection, 4 while however, most active ingredients of pesticides are lost through off-target delivery and uncontrolled release. 5,6 Recently, by applying the strategies to develop responsive nanomedicines, 7 researchers enable the release of an active ingredient of pesticide from a reservoir artificially manipulated by means of different trigger such as light, [8][9][10] temperature, [11][12][13][14] pH [15][16][17] and chemicals, 18,19 which allows the targeted plants treated with pesticide at the right time and at the right dose. These smart or intelligent pesticides are typically made of an active pesticide ingredient and an engineered carrier capable of changing or reacting in response to a specific stimulus.…”