Construction of enzyme-encapsulated fibermats from the cross-linkable copolymers poly(acrylamide)-co-poly(diacetone acrylamide) with the bi-functional cross-linker, adipic acid dihydrazide

Self-Healable and Super-Tough Double-Network Hydrogel Fibers from Dynamic Acylhydrazone Bonding and Supramolecular Interactions

“…By calculating the integral area in the NMR curve (peak 1 = 33.5, peak 5 = 224.0), the molar percentage of DAAM was calculated as 4.98% (equal to peak1 divided by peak5 three times), which is close to the feeding ratio (5.00%). This small difference is attributed to the similar reactivity of AM and DAAM in radical polymerization [ 48 ]. Furthermore, the weight average molecule weight (Mw) and polydispersity index (PDI) of the copolymers were determined via gel permeation chromatography (GPC) ( Table S1 ).…”

Electrospinning based on benign solvents: current definitions, implications and strategies

“…254 When utilizing ketone precursors, as with poly(acrylamide)- co -poly(diacetone acrylamide), the reaction proceeded slightly slower in the presence of a di-functional cross-linker, adipic dihydrazide, thus enabling the production of fibers with diameters of 200–220 nm by precursor mixing before usage. 255…”

“…254 When utilizing ketone precursors, as with poly(acrylamide)-copoly(diacetone acrylamide), the reaction proceeded slightly slower in the presence of a di-functional cross-linker, adipic dihydrazide, thus enabling the production of fibers with diameters of 200-220 nm by precursor mixing before usage. 255 A new concept in the field of reactive ES for tissue engineering has been proposed by Davidson et al, where fiber-to-fiber cross-linking could be triggered by mechanical loading, therewith mimicking the force-responsive properties of the extra-cellular matrix. 205 To achieve this novel mechano-sensitive hydrogel, they have utilized hyaluronic acid as a functional polymer for the selective attachment of aldehyde or hydrazide units.…”

Characterization of electrospun polylactide nanofibers modified via atom transfer radical polymerization

“…Nowadays, electrospinning technology has been largely applied in the areas of battery electrode materials [6], sensors [7], tissue engineering scaffold [8], and drug carrier [9] that rely upon on manageable fiber diameter, high specific surface area, high porosity and cost-effective. With the progress of research, further materials including high polymers, inorganic fillers, and so on were used in the fabrication of nanofibers by electrospinning [1,2].…”

“…A vast field of research has been done to modify it and made it usable for different applications including biomedical fields. Its physical and mechanical properties can be deployed with its polymer architecture [2].…”