The Occupational Health and Safety Program (OHS) is a method attempting to lower the risk of accidents and occupational diseases. The OHS is aimed at reducing the risks of occupational diseases and accidents in the small and medium-enterprises (SME) sector. This study aims to see the gaps in OHS that only focused on medium-sized industries so that the SME sector does not experience the effects of OHS. In-depth and systematic literature reviews were conducted, and the classification of the disaster type and its object from those sources was performed. The results show that there are gaps in the OHS, which can be seen both from the mitigation and identification methods used, which open up opportunities for further research, especially in the development of new investigative methods, as well as to improve the design of protection systems. The findings of this study will be the latest research based on perspectives in the global scope by looking at the relevant perspectives that have been run and compared systematically to be able to create opportunities for the updating of the risk mitigation process OHS in SME industrial sector.